Diphenylmethane

Diphenylmethane

SCHEMBL4416804

NNC(=O)CCNCCC(=O)NN.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
LTA4H P09960 6/20 0.50
KMT2A Q03164 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C19 P33261 2/20 0.49
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
MEN1 O00255 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
CALM1 P0DP23 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4413773 0.85 L3MBTL1 (0.55) L3MBTL1KMT2ACYP1A2CYP3A4CYP2D6
Diphenylmethane SCHEMBL4409654 0.85 L3MBTL1 (0.55) L3MBTL1LTA4HKMT2ACYP1A2CYP3A4
Benzene SCHEMBL4409529 0.84 KDM4E (0.54) L3MBTL1KMT2ACYP1A2CYP3A4CYP2D6
Diphenylmethane SCHEMBL3685483 0.78 PLA2G10 (0.57) KMT2ACYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL4411483 0.77 HDAC3 (0.44) L3MBTL1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL967387 0.77 HDAC2 (0.68) L3MBTL1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL4421124 0.76 KDM4E (0.52) L3MBTL1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL4409653 0.75 POLB (0.46) L3MBTL1LTA4HKMT2ACYP1A2CYP3A4
SCHEMBL6937640 0.74 HDAC1 (0.70) L3MBTL1HDAC8HDAC6HDAC1HDAC2
SCHEMBL1627561 0.74 L3MBTL1 (0.65) L3MBTL1KMT2ACYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed