Biphenyl

Biphenyl

SCHEMBL4411169

NCCC(=O)NN.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.58
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 2/20 0.55
CYP2C19 P33261 2/20 0.55
SMYD3 Q9H7B4 1/20 0.50
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 2/20 0.46
KDM5C P41229 1/20 0.46
PHF8 Q9UPP1 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
AOC3 Q16853 2/20 0.45
MMP2 P08253 1/20 0.45
MEN1 O00255 1/20 0.44
GAA P10253 2/20 0.44
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.43
MITF O75030 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL4411983 0.87 KDM4E (0.59) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Biphenyl SCHEMBL4413773 0.84 L3MBTL1 (0.55) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Diphenylmethane SCHEMBL4409654 0.84 L3MBTL1 (0.55) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL1542706 0.82
Carbamic Acid SCHEMBL30312208 0.80 KDM4E (0.56) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Biphenyl SCHEMBL29081077 0.78 FFAR1 (0.59) L3MBTL1CYP1A2CYP2D6CYP2C19KMT2A
Biphenyl SCHEMBL5574503 0.77 ALDH1A1 (0.50) KMT2AKDM4EMEN1GAAALDH1A1
SCHEMBL6869213 0.76 KMT2A (0.66) KMT2AKDM4EMEN1GAAALDH1A1
SCHEMBL967387 0.75 HDAC2 (0.68) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Biphenyl SCHEMBL11033740 0.75 TSHR (0.53) L3MBTL1CYP1A2CYP3A4CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed