Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695899 | 0.86 | RAB9A (0.75) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7293767 | 0.80 | RAB9A (0.72) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1687778 | 0.80 | RAB9A (0.72) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5174946 | 0.79 | RAB9A (0.75) | RAB9AMAPTNPC1SMN1; SMN2TRPV1 | |
| SCHEMBL5333874 | 0.78 | NPC1 (0.77) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27179668 | 0.77 | RAB9A (0.90) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5224127 | 0.76 | RAB9A (0.57) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4486236 | 0.74 | RAB9A (0.80) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28563049 | 0.74 | TRPV1 (0.59) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14825198 | 0.74 | ALDH1A1 (0.76) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |