SCHEMBL4409844

SCHEMBL4409844

Fc1ccc(C(F)(F)I)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
KIF11 P52732 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22409533 0.82 CES2 (0.36) CES2CES1
SCHEMBL8160495 0.79 PDE2A (0.40) CES2CES1KIF11
SCHEMBL206670 0.77 CES2 (0.41) CES2CES1KIF11
SCHEMBL578143 0.77 CES2 (0.36) CES2CES1
SCHEMBL2974322 0.75 CES2 (0.39) CES2CES1KIF11
SCHEMBL2074175 0.75 CES2 (0.34) CES2CES1
SCHEMBL6936394 0.75 CES2 (0.34) CES2CES1KIF11
SCHEMBL1201613 0.75 CES2 (0.39) CES2CES1KIF11
SCHEMBL11255717 0.75 CES2 (0.34) CES2CES1
SCHEMBL2973848 0.75 CES2 (0.34) CES2CES1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598329-B2 Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts TICONA GMBH (DE) 2009-10-06 US disclosed
US-20070105712-A1 Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2007-05-10 US disclosed
US-20030139600-A1 2-pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL CO., LTD. 2003-07-24 US disclosed
US-6548673-B1 Alkylation using transition metal complex catalyst; purified by acid/base extraction SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed
US-6531602-B2 Desilylation of a 2-pyridylsilane to form an alcohol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-11 US disclosed
US-20020165397-A1 2-Pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL CO., LTD. 2002-11-07 US disclosed
EP-1035125-A2 2-Pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-13 EP disclosed
EP-0363987-B1 Organic fluorine compound MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1996-02-28 EP disclosed
EP-0554029-B1 Oral compositions SUNSTAR KK (JP) 1995-09-20 EP disclosed
US-5348738-A With quaternary nitrogen atoms and, as stabilizer for the polymer, polyoxyethylene-polyoxypropylene block copolymer surfactant SUNSTAR KABUSHIKI KAISHA (JP) 1994-09-20 US disclosed
EP-0554029-A1 Oral compositions SUNSTAR KABUSHIKI KAISHA (JP) 1993-08-04 EP disclosed
US-5057623-A Magnetic coating material dispersants MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-10-15 US disclosed
EP-0363987-A2 Organic fluorine compound MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-04-18 EP disclosed
EP-0360276-A2 Microbial adsorbent and microbial sensor using the same KAO CORPORATION (JP) 1990-03-28 EP disclosed
WO-1988006732-A1 TAGGED BINDING REAGENTS AND METHODS FOR DETECTING TARGET ANALYTES ALLIED CORPORATION (US) 1988-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165397-A1 2-Pyridylsilane, processes for producing and using the same H1-0, RIOK2, H1-4 CES2 2284/4885CES1 2946/4885KIF11 1481/4885
US-20030139600-A1 2-pyridylsilane, processes for producing and using the same H1-0, H1-4, H1-2 CES2 2488/4885CES1 3105/4885KIF11 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.