SCHEMBL8160495

SCHEMBL8160495

Fc1ccc(C(F)(F)F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.40
KIF11 P52732 10/20 0.39
CES2 O00748 2/20 0.37
CES1 P23141 1/20 0.37
KDM1A O60341 1/20 0.35
HSD11B1 P28845 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
MPL P40238 3/20 0.32
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206670 0.81 CES2 (0.41) KIF11CES2CES1
SCHEMBL578143 0.81 CES2 (0.36) CES2CES1
SCHEMBL11255717 0.79 CES2 (0.34) CES2CES1TSHR
SCHEMBL2973848 0.79 CES2 (0.34) KIF11CES2CES1
SCHEMBL6936394 0.79 CES2 (0.34) KIF11CES2CES1MPL
SCHEMBL1201613 0.79 CES2 (0.39) PDE2AKIF11CES2CES1
SCHEMBL4409844 0.79 CES2 (0.34) KIF11CES2CES1
SCHEMBL15850520 0.79 KIF11 (0.36) PDE2AKIF11KDM1ACYP11B1CYP11B2
SCHEMBL2974322 0.79 CES2 (0.39) KIF11CES2CES1
SCHEMBL2074175 0.79 CES2 (0.34) CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333793-B Multi-element triblock fluorosilicone copolymer electronic protective agent with sequence structure and preparation method thereof 山东应强新材料科技有限公司 2022-12-13 CN claimed
CN-109535902-B Preparation method of super-amphiphobic coating for surface of wood-plastic composite material 西安理工大学 2021-01-15 CN claimed
CN-111333793-A Multi-element triblock fluorosilicone copolymer electronic protective agent with sequence structure and preparation method thereof 山东应强新材料科技有限公司 2020-06-26 CN claimed
CN-108948939-B Multifunctional electronic protective coating composition with low dielectric constant 黑龙江泰纳科技发展股份有限公司 2020-04-10 CN claimed
CN-110079181-A A kind of preparation method of environmental response type super-amphiphobic coating 西安理工大学 2019-08-02 CN claimed
CN-109535902-A A kind of preparation method of the super-amphiphobic coating for surface of wood-plastic composite material 西安理工大学 2019-03-29 CN claimed
CN-108948939-A A kind of low-k multifunction electronic protective coating composition 黑龙江泰纳科技发展股份有限公司 2018-12-07 CN claimed
CN-107805434-A A kind of fluorescent type electronic protection coating and preparation method thereof 浙江大学 2018-03-16 CN claimed
CN-107699099-A A kind of fluorescent visual type electronic protection coating composition and preparation method thereof 浙江大学 2018-02-16 CN claimed
CN-119812190-A Electrode for battery, and method for manufacturing electrode for battery 丰田自动车株式会社 2025-04-11 CN disclosed
CN-118160076-B Etching gas and etching method using the same 大金工业株式会社 2024-08-27 CN disclosed
CN-118507665-A Nonaqueous electrolyte secondary battery 丰田自动车株式会社 2024-08-16 CN disclosed
CN-118248848-A Negative electrode active material, nonaqueous electrolyte secondary battery, and method for producing negative electrode active material 丰田自动车株式会社 2024-06-25 CN disclosed
CN-118160076-A Etching gas and etching method using the same 大金工业株式会社 2024-06-07 CN disclosed
EP-0006354-B1 FLUORO-SUBSTITUTED PYRETHROID-TYPE ESTERS, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES FOR USE IN SUCH PROCESSES, COMPOSITIONS FOR INSECTICIDAL USE, AND METHODS OF COMBATING INSECT PESTS ICI AUSTRALIA LIMITED (AU) 1984-09-26 EP disclosed
EP-0034402-B1 METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-29 EP disclosed
EP-0113625-A1 Process for the preparation of trifluoromethylated benzenic compounds RHONE-POULENC CHIMIE (FR) 1984-07-18 EP disclosed
US-4376784-A Pesticidal fluorinated esters of the pyrethrin or pyrethroid type ICI AUSTRALIA LIMITED (AU) 1983-03-15 US disclosed
US-4283414-A Pesticidal fluorinated esters of the pyrethrin or pyrethroid type ICI AUSTRALIA LIMITED (AU) 1981-08-11 US disclosed
EP-0006354-A1 Fluoro-substituted pyrethroid-type esters, processes for their preparation, intermediates for use in such processes, compositions for insecticidal use, and methods of combating insect pests ICI AUSTRALIA LIMITED (AU) 1980-01-09 EP disclosed