Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2987321 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| Sulfuric Acid SCHEMBL6947452 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL9658374 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| Sulfuric Acid SCHEMBL10790443 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL27511437 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL10766337 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL9489956 | 0.72 | RAPGEF4 (0.43) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| Sulfuric Acid SCHEMBL94577 | 0.71 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| Sulfuric Acid SCHEMBL479273 | 0.71 | CYP3A4 (1.00) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| Sulfuric Acid SCHEMBL9317897 | 0.71 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7637962-B2 | Multicomponent kit and method for dyeing keratin fibers | WELLA AG (DE) | 2009-12-29 | — | — | US | disclosed |
| US-20080263786-A1 | Multicomponent Kit and Method for Dyeing Keratin Fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-30 | — | — | US | disclosed |
| EP-1771226-B1 | MULTICOMPONENT KIT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080263786-A1 | Multicomponent Kit and Method for Dyeing Keratin Fibers | KRT18, KIT, CKMT1A; CKMT1B | ALDH1A1 761/4885TSHR 4674/4885CYP3A4 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.