SCHEMBL4410319

SCHEMBL4410319

CCC(=O)Nc1cc2ccccc2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.49
GRIK1 P39086 1/20 0.48
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 2/20 0.47
MAPK1 P28482 1/20 0.47
DRD3 P35462 1/20 0.47
FLT3 P36888 1/20 0.46
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 3/20 0.45
DAO P14920 1/20 0.45
SRD5A2 P31213 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34461886 1.00 DRD2 (0.49) DRD2GRIK1KDM4EALDH1A1GAA
SCHEMBL5142086 0.85 GRIK1 (0.49) DRD2GRIK1KDM4EALDH1A1GAA
SCHEMBL8102853 0.83 SPHK2 (0.60) DRD2KDM4EALDH1A1DRD3SMN1; SMN2
SCHEMBL31487774 0.81 MTNR1A (0.53) DRD2GRIK1KDM4EALDH1A1GAA
SCHEMBL4413986 0.81 MTNR1A (0.53) DRD2GRIK1KDM4EALDH1A1GAA
SCHEMBL27014631 0.81 CYP1A2 (0.54) GRIK1KDM4EALDH1A1GAAMAPK1
SCHEMBL8118597 0.81 KDM4E (0.45) DRD2GRIK1KDM4EALDH1A1GAA
SCHEMBL12848262 0.80 CYP2A6 (0.46) KDM4EALDH1A1GAASMN1; SMN2RAB9A
SCHEMBL22230602 0.80 RAB9A (0.50) GRIK1KDM4EALDH1A1GAAMAPK1
SCHEMBL9269321 0.80 GRIK1 (0.56) DRD2GRIK1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
EP-1001934-A1 INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER PHARMACEUTICALS INC. (JP) 2000-05-24 EP disclosed
WO-1999005104-A1 INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER PHARMACEUTICALS INC. (JP) 1999-02-04 WO disclosed