Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403262 | 0.92 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL4410325 | 0.89 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL4296532 | 0.86 | DGAT1 (0.76) | DGAT1 | |
| SCHEMBL4403258 | 0.81 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL4410322 | 0.80 | DGAT1 (0.65) | DGAT1 | |
| SCHEMBL4291947 | 0.78 | DGAT1 (0.74) | DGAT1 | |
| SCHEMBL4289819 | 0.77 | DGAT1 (0.75) | DGAT1 | |
| SCHEMBL4289322 | 0.76 | DGAT1 (0.73) | DGAT1 | |
| SCHEMBL4293205 | 0.74 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL4570516 | 0.73 | DGAT1 (0.90) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |