Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907329 | 0.87 | HDAC8 (0.50) | GRM5APPHDAC8PIK3CDPIK3CA | |
| SCHEMBL31510376 | 0.86 | GRM5 (0.50) | GRM5HAO1 | |
| SCHEMBL4312379 | 0.85 | GRM5 (0.47) | GRM5APPHDAC8HAO1PIK3CD | |
| SCHEMBL27952686 | 0.85 | CA12 (0.53) | GRM5HAO1 | |
| SCHEMBL2925968 | 0.84 | APP (0.67) | GRM5APPHDAC8PIK3CDPIK3CA | |
| SCHEMBL1820120 | 0.84 | HDAC8 (0.58) | GRM5APPHDAC8PIK3CDPIK3CA | |
| SCHEMBL4324850 | 0.83 | ASIC3 (0.53) | GRM5APPHAO1PIK3CDPIK3CA | |
| SCHEMBL17224548 | 0.82 | APP (0.63) | GRM5APPHDAC8PIK3CDPIK3CA | |
| SCHEMBL1649302 | 0.81 | HDAC8 (0.55) | GRM5APPHDAC8PIK3CDPIK3CA | |
| SCHEMBL12873256 | 0.81 | ASIC3 (0.56) | GRM5APPHAO1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318663-A1 | Polymerizable Spherical Transition Metal Complex, Spherical Transition Metal Complex, and Production Method Thereof | UNIVERSITY OF TOKYO, THE (JP) | 2009-12-24 | — | — | US | disclosed |