Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410503 | 1.00 | NLRP3 (0.36) | NLRP3KMT2ATDP1ALDH1A1CYP2D6 | |
| SCHEMBL3502256 | 0.88 | NLRP3 (0.36) | NLRP3KMT2ATDP1ALDH1A1CYP2D6 | |
| SCHEMBL3502251 | 0.88 | NLRP3 (0.36) | NLRP3KMT2ATDP1ALDH1A1CYP2D6 | |
| SCHEMBL13311887 | 0.74 | PTGER4 (0.41) | TDP1ALDH1A1NPSR1POLBPTGER4 | |
| SCHEMBL4405462 | 0.74 | ALDH1A1 (0.40) | ALDH1A1NPSR1POLBPTGER4PTGER2 | |
| SCHEMBL6009101 | 0.70 | FFAR1 (0.46) | PTPN22 | |
| SCHEMBL6009093 | 0.70 | FFAR1 (0.46) | PTPN22 | |
| SCHEMBL3624445 | 0.69 | PTPN22 (0.40) | PTPN22 | |
| SCHEMBL3624441 | 0.69 | PTPN22 (0.40) | PTPN22 | |
| SCHEMBL6009129 | 0.69 | FFAR1 (0.45) | KMT2AALDH1A1PTPN22MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |