Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502251 | 1.00 | NLRP3 (0.36) | NLRP3KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL4410503 | 0.88 | NLRP3 (0.36) | NLRP3KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL4410501 | 0.88 | NLRP3 (0.36) | NLRP3KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL3503152 | 0.75 | PTGER4 (0.39) | PTGER4PTGER2 | |
| SCHEMBL3632754 | 0.71 | FFAR1 (0.39) | PTPN22 | |
| SCHEMBL3632751 | 0.71 | FFAR1 (0.39) | PTPN22 | |
| SCHEMBL3629045 | 0.70 | PTPN22 (0.32) | KMT2AMEN1NPSR1ALDH1A1PTPN22 | |
| SCHEMBL3629043 | 0.70 | PTPN22 (0.32) | KMT2AMEN1NPSR1ALDH1A1PTPN22 | |
| SCHEMBL3627665 | 0.70 | FFAR1 (0.37) | KMT2AMEN1NPSR1PTPN22 | |
| SCHEMBL3627662 | 0.69 | FFAR1 (0.42) | KMT2AMEN1NPSR1ALDH1A1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | NLRP3 576/4885KMT2A 3440/4885MEN1 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.