Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 16/20 | 0.61 |
| ▸ | PSEN2 | P49810 | 16/20 | 0.61 |
| ▸ | APH1B | Q8WW43 | 16/20 | 0.61 |
| ▸ | NCSTN | Q92542 | 16/20 | 0.61 |
| ▸ | APH1A | Q96BI3 | 16/20 | 0.61 |
| ▸ | PSENEN | Q9NZ42 | 16/20 | 0.61 |
| ▸ | CNR2 | P34972 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529516 | 0.93 | PSEN1 (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5514950 | 0.86 | PSEN1 (0.60) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL551644 | 0.84 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14107129 | 0.84 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9905344 | 0.84 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9976723 | 0.84 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1001993 | 0.83 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6275417 | 0.83 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1000878 | 0.83 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6575875 | 0.83 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660450-A4 | MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES | UNIV LAVAL (CA) | 2009-07-29 | — | — | EP | disclosed |
| US-20070069197-A1 | Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles | UNIVERSITE LAVAL (CA) | 2007-03-29 | — | — | US | disclosed |
| EP-1660450-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES | Université Laval (CA) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016882-A1 | MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES | UNIVERSITE LAVAL (CA) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070069197-A1 | Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles | TELO2, DNMT1, DDT | PSEN1 4166/4885PSEN2 3936/4885APH1B 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.