SCHEMBL441128

SCHEMBL441128

Cc1c(F)c(F)c(COC(=O)C2C(C=C(Cl)Cl)C2(C)C)c(F)c1F

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.80
TDP1 Q9NUW8 4/20 0.80
MEN1 O00255 4/20 0.80
LMNA P02545 7/20 0.48
ATM Q13315 2/20 0.48
ADRA2A P08913 1/20 0.48
CNR1 P21554 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 3/20 0.47
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8456259 1.00 KMT2A (0.80) KMT2ATDP1MEN1LMNAATM
SCHEMBL7527695 1.00 KMT2A (0.80) KMT2ATDP1MEN1LMNAATM
SCHEMBL29843295 0.95 KMT2A (0.73) KMT2ATDP1MEN1LMNAATM
Fenfluthrin SCHEMBL10608263 0.93 KMT2A (0.70) KMT2ATDP1MEN1LMNAATM
Fenfluthrin SCHEMBL9322107 0.93 KMT2A (0.70) KMT2ATDP1MEN1LMNAATM
Fenfluthrin SCHEMBL5706649 0.93 KMT2A (0.70) KMT2ATDP1MEN1LMNAATM
Fenfluthrin SCHEMBL73318 0.93 KMT2A (0.70) KMT2ATDP1MEN1LMNAATM
SCHEMBL29911478 0.93 KMT2A (0.70) KMT2ATDP1MEN1LMNAATM
SCHEMBL15996435 0.92 TDP1 (0.77) KMT2ATDP1MEN1LMNAATM
SCHEMBL2741340 0.92 TDP1 (0.77) KMT2ATDP1MEN1LMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459168-B2 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2008-12-02 US claimed
EP-1352562-B1 Insecticide transpiration apparatus DAINIPPON JOCHUGIKU KK (JP) 2006-11-15 EP claimed
US-6926902-B2 Insecticide transpiration apparatus DAINHON JOCHUGIKU CO., LTD. (JP) 2005-08-09 US claimed
US-20040180070-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2004-09-16 US claimed
EP-1352562-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-10-15 EP claimed
US-20030160062-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-08-28 US claimed
JP-11335331-A None JP disclosed
US-9238078-B2 Modified-release pharmaceutical drug composition COATING PLACE, INC. (US) 2016-01-19 US disclosed
US-9125948-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2015-09-08 US disclosed
US-8883213-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2014-11-11 US disclosed
EP-2685830-A1 PEST CONTROL COMPOSITION AND PEST CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2014-01-22 EP disclosed
US-20130345266-A1 PEST CONTROL COMPOSITION AND PEST CONTROL METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-26 US disclosed
US-8343546-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2013-01-01 US disclosed
EP-0959065-B1 Pyrethroid compound and composition for controlling pest containing the same SUMITOMO CHEMICAL CO (JP) 2002-04-03 EP disclosed
US-6352693-B1 PESTICIDE, CARRAGEENAN, AND GLYCERIN IN A POWDERED CROP, DEXTRIN, A SUGAR, A FAT AND/OR A FATTY OIL; CONTROLLING ANTS AND COCKROACHES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-05 US disclosed
JP-2002060305-A PEST-CONTROLLING MATERIAL SUMIKA LIFE TECH CO LTD 2002-02-26 JP disclosed
JP-H11335331-A PYRETHROID COMPOUND AND INSECT PEST CONTROLLING AGENT CONTAINING THE SAME COMPOUND SUMITOMO CHEM CO LTD 1999-12-07 JP disclosed
EP-0959065-A1 Pyrethroid compound and composition for controlling pest containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-24 EP disclosed
US-5885606-A Poison bait for controlling pest insects SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-23 US disclosed
US-5707639-A Solid insect growth regulating compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180070-A1 Insecticide transpiration apparatus TIMM13, PIK3C3, ATP5PD KMT2A 3655/4885TDP1 2733/4885MEN1 4117/4885
US-20030160062-A1 Insecticide transpiration apparatus PIK3C3, ACHE, ATP5PD KMT2A 4329/4885TDP1 1190/4885MEN1 4401/4885
US-20130345266-A1 PEST CONTROL COMPOSITION AND PEST CONTROL METHOD CTRL, CRY1, TET1 KMT2A 630/4885TDP1 1790/4885MEN1 1045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.