SCHEMBL4411762

SCHEMBL4411762

N#Cc1cccc(CON)c1F

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.48
AGXT P21549 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9948155 0.82 ALDH1A1 (0.38)
SCHEMBL19234559 0.81 PNMT (0.39)
SCHEMBL1715776 0.81 IDO1 (0.50) IDO1
SCHEMBL16960569 0.79 TSHR (0.34)
Hydrochloric Acid SCHEMBL25370715 0.79 PNMT (0.38)
Hydrochloric Acid SCHEMBL30580143 0.79 PNMT (0.38)
SCHEMBL15018243 0.76 PTGDR2 (0.41)
SCHEMBL15018240 0.76 NOTUM (0.36)
SCHEMBL12648422 0.76 GABRA1 (0.40)
SCHEMBL24108195 0.76 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2040698-A2 OXIME COMPOUNDS AND THE USE THEREOF SHIONOGI & CO., LTD. (JP) 2009-04-01 EP disclosed
WO-2008008398-A2 OXIME COMPOUNDS AND THE USE THEREOF SHIONOGI & CO., LTD. (JP) 2008-01-17 WO disclosed