Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409353 | 0.79 | RAB9A (0.41) | SCDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5379544 | 0.74 | SCD (0.46) | SCDCHEK2ALDH1A1PARP10PARP15 | |
| SCHEMBL30489440 | 0.74 | PSMB8 (0.50) | SCDALDH1A1S1PR3RAB9AS1PR1 | |
| SCHEMBL21317604 | 0.74 | PSMB8 (0.50) | SCDALDH1A1S1PR3RAB9AS1PR1 | |
| SCHEMBL12467073 | 0.73 | EPHX2 (0.40) | F2RL1SCDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15273772 | 0.73 | SCD (0.36) | SCDALDH1A1SMN1; SMN2 | |
| SCHEMBL5782512 | 0.73 | RAB9A (0.37) | HTR6ALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL2528074 | 0.70 | PPARA (0.40) | CHEK2ALDH1A1S1PR3RAB9AS1PR1 | |
| SCHEMBL4167072 | 0.70 | CAPN1 (0.36) | SCDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25180195 | 0.69 | LMNA (0.36) | SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |