Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.75 |
| ▸ | GRM6 | O15303 | 2/20 | 0.75 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.75 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.75 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.75 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.75 |
| ▸ | GSR | P00390 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.75 |
| ▸ | GRM5 | P41594 | 1/20 | 0.75 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.75 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.75 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.75 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.75 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.75 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.75 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.75 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.75 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.75 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystine SCHEMBL5595794 | 1.00 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GRIN2D | |
| Cystine SCHEMBL441237 | 1.00 | GRM8 (0.75) | GRM8GRM6GRM7GRM4GRIN2D | |
| Cystine SCHEMBL20551359 | 0.94 | GRM8 (0.67) | GRM8GRM6GRM7GRM4GRIN2D | |
| Cystine SCHEMBL4890271 | 0.89 | GRM8 (0.56) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL26698369 | 0.87 | GRM8 (0.90) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL3661546 | 0.87 | GRM8 (0.90) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL19900160 | 0.87 | GRM8 (0.90) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL26621747 | 0.87 | GRM8 (0.90) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamic Acid SCHEMBL2683411 | 0.87 | GRM8 (0.90) | GRM8GRM6GRM7GRM4GRIN2D | |
| D-Glutamate SCHEMBL1330484 | 0.87 | GRM8 (1.00) | GRM8GRM6GRM7GRM4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272421-A | Method for generating tumor infiltrating lymphocytes and use thereof in immunotherapy | 艾欧凡斯生物治疗公司 | 2021-08-17 | — | — | CN | claimed |
| US-20180371643-A1 | Method of Identification of Combinatorial Enzymatic Reaction Targets in Glioblastoma Specific Metabolic Network | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-12-27 | — | — | US | claimed |
| WO-2017094025-A1 | METHOD OF IDENTIFICATION OF COMBINATORIAL ENZYMATIC REACTION TARGETS IN GLIOBLASTOMA SPECIFIC METABOLIC NETWORK | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-08 | — | — | WO | claimed |
| CN-101019530-A | Azacycle containing pesticide microemulsion and its prepn | ZHOU BENXIN (CN) | 2007-08-22 | — | — | CN | claimed |
| US-20250282720-A1 | ALKYLSULFENYL THIOCARBONATES: PRECURSORS TO HYDROPERSULFIDES POTENTLY ATTENUATE OXIDATIVE STRESS | THE JOHNS HOPKINS UNIVERSITY | 2025-09-11 | — | — | US | disclosed |
| CN-118932033-A | High-sensitivity drug screening platform based on piggyBac transposition system and application thereof | 中国药科大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-118453649-A | Application of iron-dead neutrophil in preparation of antitumor drugs | 苏州大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-114948943-B | New application of large calyx variant A | 湖北医药学院 | 2024-03-08 | — | — | CN | disclosed |
| CN-115089723-B | Glutathione and hydrogen peroxide sensitive manganese-based nanoparticle as well as preparation method and application thereof | 中山大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-110707221-B | Application of amino acid ionic liquid in preparation of perovskite layer in perovskite photoelectric device | 北京大学深圳研究生院 | 2023-09-01 | — | — | CN | disclosed |
| WO-2022232622-A1 | ALKYLSULFENYL THIOCARBONATES: PRECURSORS TO HYDROPERSULFIDES POTENTLY ATTENUATE OXIDATIVE STRESS | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-11-03 | — | — | WO | disclosed |
| CN-115089723-A | Glutathione and hydrogen peroxide sensitive manganese-based nanoparticles and preparation method and application thereof | 中山大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-107735094-A | New use of inhibitors of cystine-glutamate transporter | 中国医药大学 | 2018-02-23 | — | — | CN | disclosed |
| WO-2017094025-A1 | METHOD OF IDENTIFICATION OF COMBINATORIAL ENZYMATIC REACTION TARGETS IN GLIOBLASTOMA SPECIFIC METABOLIC NETWORK | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-08 | — | — | WO | disclosed |
| US-20130296185-A1 | TAPE STRIPPING METHODS FOR ANALYSIS OF SKIN DISEASE AND PATHOLOGICAL SKIN STATE | DERMTECH INTERNATIONAL (US) | 2013-11-07 | — | — | US | disclosed |
| US-20120065086-A1 | Tape stripping methods for analysis of skin desease and pathological skin state | DERMTECH, LLC | 2012-03-15 | — | — | US | disclosed |
| US-20120046232-A1 | COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2012-02-23 | — | — | US | disclosed |
| CN-101019530-A | Azacycle containing pesticide microemulsion and its prepn | ZHOU BENXIN (CN) | 2007-08-22 | — | — | CN | disclosed |
| US-RE39734-E1 | Selenium source, a glutathione precursor of glutamic acid, cystine and glycine; increasing the content of glutathione in body tissue above that of a pretreatment level, enhancing immune activity | CRUM ALBERT | 2007-07-17 | — | — | US | disclosed |
| US-4767748-A | Substituted oligosaccharide antibodies | SCHERING CORPORATION (US) | 1988-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046232-A1 | COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR | GRM6, GRM5, GRM7 | GRM8 17/4885GRM6 1/4885GRM7 3/4885 |
| US-20250282720-A1 | ALKYLSULFENYL THIOCARBONATES: PRECURSORS TO HYDROPERSULFIDES POTENTLY ATTENUATE OXIDATIVE STRESS | FECH, HAGH, TST | GRM8 3316/4885GRM6 2361/4885GRM7 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.