Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698948 | 0.90 | KDM4E (0.50) | NPC1MAPTHDAC1THRATP53 | |
| SCHEMBL4411549 | 0.86 | CA1 (0.56) | NPC1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL5693951 | 0.85 | NPC1 (0.56) | NPC1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL4418967 | 0.82 | MMP3 (0.55) | MAPTCA1CA2HDAC1HDAC3 | |
| SCHEMBL4411547 | 0.81 | MMP3 (0.54) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4414363 | 0.80 | GAA (0.51) | MAPTSMN1; SMN2 | |
| SCHEMBL808434 | 0.79 | MPO (0.58) | NPC1MAPTCA1CA2HDAC1 | |
| SCHEMBL4072168 | 0.78 | CA1 (0.54) | NPC1MAPTCA1CA2ALDH1A1 | |
| SCHEMBL4411183 | 0.78 | KDM4E (0.58) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5693970 | 0.76 | CA1 (0.71) | NPC1MAPTCA1CA2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638565-B2 | Polyacetal resin composition | POLYPLASTICS CO., LTD. (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20070054998-A1 | Polyacetal resin composition | POLYPLASTICS CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |