SCHEMBL4412947

SCHEMBL4412947

CC(C(=O)NN)N1C(=O)c2ccc(C(=O)NN)cc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.47
MAPK1 P28482 2/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALOX15 P16050 1/20 0.45
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11150999 0.72 MAPK1 (0.60) MAPK1KMT2AMEN1
SCHEMBL12921585 0.70 SMN1; SMN2 (0.60) ALDH1A1MAPK1HTTSMN1; SMN2ALOX15
SCHEMBL4412960 0.70 ALDH1A1 (0.50) ALDH1A1MAPK1SMN1; SMN2KMT2AMEN1
SCHEMBL901071 0.70 ALDH1A1 (0.35) ALDH1A1MAPK1HTTSMN1; SMN2ALOX15
SCHEMBL15623831 0.70 POLB (0.55) MAPK1KMT2AMEN1
SCHEMBL20657130 0.69 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1GAA
SCHEMBL15762473 0.69 ALDH1A1 (0.51) ALDH1A1MAPK1KMT2AMEN1LMNA
SCHEMBL10416266 0.69 TTR (0.62) ALDH1A1KMT2AMEN1GAAHPGD
Hydrochloric Acid SCHEMBL31573869 0.69 ALDH1A1 (0.34) ALDH1A1MAPK1HTTSMN1; SMN2ALOX15
SCHEMBL31085044 0.68 S100A4 (0.53) MAPK1SMN1; SMN2KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed