SCHEMBL4412960

SCHEMBL4412960

NNC(=O)CCN1C(=O)c2ccc(C(=O)NN)cc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.50
TSHR P16473 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
MAPK1 P28482 1/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
RECQL P46063 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4409652 0.82 POLB (0.63) ALDH1A1TSHRMEN1KMT2AHSD17B10
SCHEMBL4235113 0.73 SMN1; SMN2 (0.78) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL30942651 0.72 POLB (0.75) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL10491219 0.72 POLB (0.75) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL4412947 0.70 ALDH1A1 (0.47) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL17897619 0.70 POLB (0.54) ALDH1A1TSHRMEN1KMT2ANPC1
SCHEMBL10491216 0.69 ALDH1A1 (0.82) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL5864233 0.68 SMN1; SMN2 (0.86) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL10632178 0.68 POLB (0.69) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL4235238 0.68 SMN1; SMN2 (0.89) ALDH1A1TSHRMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed