Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.52 |
| ▸ | GLA | P06280 | 9/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669385 | 0.78 | MCL1 (0.56) | GAAALDH1A1KDM4EGLAHIF1A | |
| SCHEMBL875961 | 0.75 | KDM4E (0.39) | GAAALDH1A1KDM4EGLAHIF1A | |
| SCHEMBL8564999 | 0.74 | KDM4E (0.38) | GAAALDH1A1KDM4EGLAHIF1A | |
| SCHEMBL8565004 | 0.74 | GAA (0.38) | GAAALDH1A1KDM4EGLAHIF1A | |
| SCHEMBL565580 | 0.73 | MCL1 (0.55) | GAAALDH1A1KDM4EGLAHPGD | |
| SCHEMBL16096924 | 0.73 | KMT2A (0.57) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8571050 | 0.73 | MET (0.51) | GAAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18073952 | 0.72 | KDM4E (0.52) | GAAALDH1A1KDM4EGLAHIF1A | |
| SCHEMBL15396964 | 0.72 | ALDH1A1 (0.46) | GAAALDH1A1KDM4EGLAHIF1A | |
| SCHEMBL15170269 | 0.72 | MCL1 (0.55) | GAAALDH1A1KDM4EGLAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660638-B1 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | INTEGRAL MOLECULAR INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-9213027-B2 | Lipoparticles comprising proteins, methods of making, and using the same | INTEGRAL MOLECULAR, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140135230-A1 | Lipoparticles Comprising Proteins, Methods Of Making, And Using The Same | INTEGRAL MOLECULAR, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-8574590-B2 | Lipoparticles comprising proteins, methods of making, and using the same | INTEGRAL MOLECULAR, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| EP-1660638-A4 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | INTEGRAL MOLECULAR INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1660638-A2 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | Integral Molecular, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20050123563-A1 | Lipoparticles comprising proteins, methods of making, and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-09 | — | — | US | disclosed |
| WO-2005042695-A2 | LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME | INTEGRAL MOLECULAR, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-5830912-A | Derivatives of 6,8-difluoro-7-hydroxycoumarin | MOLECULAR PROBES, INC. (US) | 1998-11-03 | — | — | US | disclosed |