SCHEMBL669385

SCHEMBL669385

O=c1cc(CCl)c2cc(F)c(O)c(F)c2o1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.56
PON1 P27169 2/20 0.46
KDM4E B2RXH2 7/20 0.41
GLA P06280 7/20 0.41
GAA P10253 7/20 0.41
ALDH1A1 P00352 6/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ERAP1 Q9NZ08 1/20 0.39
HPGD P15428 4/20 0.38
HIF1A Q16665 3/20 0.38
DYRK1A Q13627 1/20 0.38
MAOB P27338 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MET P08581 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
B-D-Galactose SCHEMBL8563122 0.84 MCL1 (0.42) MCL1PON1KDM4EGLAGAA
SCHEMBL875961 0.81 KDM4E (0.39) MCL1KDM4EGLAGAAALDH1A1
SCHEMBL8565004 0.80 GAA (0.38) MCL1KDM4EGLAGAAALDH1A1
SCHEMBL8564999 0.80 KDM4E (0.38) MCL1KDM4EGLAGAAALDH1A1
SCHEMBL8571050 0.79 MET (0.51) MCL1KDM4EGAAALDH1A1HSD17B10
SCHEMBL15170269 0.78 MCL1 (0.55) MCL1KDM4EGLAGAAALDH1A1
SCHEMBL4413285 0.78 GAA (0.52) KDM4EGLAGAAALDH1A1CASP1
SCHEMBL29391372 0.76 MCL1 (0.55) MCL1KDM4EGLAGAAALDH1A1
SCHEMBL565580 0.76 MCL1 (0.55) MCL1KDM4EGLAGAAALDH1A1
SCHEMBL8570582 0.74 CSNK2A2 (0.51) MCL1KDM4EGAAALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2820147-B1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING HARVARD COLLEGE (US) 2018-08-08 EP claimed
US-9632085-B2 Rapid antibiotic susceptibility testing PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-04-25 US claimed
US-20150064703-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2015-03-05 US claimed
EP-2820147-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING President and Fellows of Harvard College (US) 2015-01-07 EP claimed
WO-2013130875-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-09-06 WO claimed
CN-1996015-A Flow cytometry biochip for use in immune monitoring and research and development of medicine LIN YUAN (CN) 2007-07-11 CN claimed
CN-1970788-A Flow cytometry and intracellular molecular probe technology ZHENG FANG (CN) 2007-05-30 CN claimed
CN-119823939-A Composition, culture solution, product and method for promoting in-vitro maturation of immature oocytes 中国农业大学 2025-04-15 CN disclosed
CN-119081996-A Application of caffeic acid phenethyl ester in preparation of product for promoting in-vitro embryo development 五邑大学 2024-12-06 CN disclosed
CN-115896007-B Application of chrysoeriol in preparation of product for promoting embryo development 五邑大学 2024-10-18 CN disclosed
CN-114410573-B Oocyte in-vitro maturation culture solution additive and application thereof 内蒙古大学 2024-09-27 CN disclosed
CN-118109393-A Application of isoorientin in preparation of product for improving quality of in-vitro embryo 五邑大学 2024-05-31 CN disclosed
CN-117860729-A Application of apigenin in preparation of medicine for delaying oocyte aging 五邑大学 2024-04-12 CN disclosed
CN-1970788-A Flow cytometry and intracellular molecular probe technology ZHENG FANG (CN) 2007-05-30 CN disclosed
US-20070082377-A1 Cytotoxicity assays IMMUNOCHEMISTRY TECHNOLOGIES, LLC 2007-04-12 US disclosed
US-20070082377-A1 Cytotoxicity assays IMMUNOCHEMISTRY TECHNOLOGIES, LLC 2007-04-12 US disclosed
EP-1060239-B1 BIOSENSOR ARRAY COMPRISING CELL POPULATIONS CONFINED TO MICROCAVITIES TUFTS COLLEGE (US) 2004-06-09 EP disclosed
US-6667159-B1 Microwell formed on the distal end of each strand formed by anisotropic etching of the core; each single cell inserted in a microwell is optically coupled and in optical communication with a fiber strand TRUSTEES OF TUFTS COLLEGE 2003-12-23 US disclosed
US-6377721-B1 Biosensor array comprising cell populations confined to microcavities TRUSTEES OF TUFTS COLLEGE 2002-04-23 US disclosed
US-5830912-A Derivatives of 6,8-difluoro-7-hydroxycoumarin MOLECULAR PROBES, INC. (US) 1998-11-03 US disclosed