Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5423626 | 0.99 | VCAM1 (0.56) | VCAM1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL259511 | 0.86 | CASP6 (0.53) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL260606 | 0.85 | KMT2A (0.64) | VCAM1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL12229762 | 0.85 | TSHR (0.59) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9081516 | 0.84 | KMT2A (0.48) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL730927 | 0.83 | VCAM1 (0.59) | VCAM1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL1142710 | 0.82 | KMT2A (0.47) | ALDH1A1LMNAMAPTMAPK1HPGD | |
| SCHEMBL1827529 | 0.82 | LMNA (0.56) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1552568 | 0.81 | LMNA (0.55) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6284647 | 0.81 | LMNA (0.58) | VCAM1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523475-B1 | HETEROCYCLICALLY SUBSTITUTED BENZOYLUREAS, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-12-23 | — | — | EP | disclosed |