Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728578 | 1.00 | POLB (0.48) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL11119821 | 0.97 | POLB (0.46) | POLBCDC25BEHMT2EHMT1MAOA | |
| Propionitrile SCHEMBL8597970 | 0.81 | DRD3 (0.46) | CASP3KMT2AMEN1CA12CA9 | |
| SCHEMBL454827 | 0.75 | POLB (0.67) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL134793 | 0.73 | POLB (0.56) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL2022462 | 0.73 | POLB (0.64) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL487827 | 0.71 | POLB (0.48) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL14410649 | 0.71 | POLB (0.48) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL1771 | 0.71 | POLB (0.48) | POLBCDC25BEHMT2EHMT1MAOA | |
| SCHEMBL7563174 | 0.71 | POLB (0.48) | POLBCDC25BEHMT2EHMT1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551023-A | Preparation method and application of N-thio-phenyl phthalimide compound | 太原理工大学 | 2024-02-13 | — | — | CN | claimed |
| CN-117447370-A | Preparation method of aggregation-induced emission material tetraaryl divinyl sulfide | 山西蓬勃健康科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-113264859-B | Naphthalene sulfonamide isothiocyanate bifunctional micromolecules as well as preparation method and application thereof | 宁夏医科大学 | 2023-02-07 | — | — | CN | claimed |
| CN-113264859-A | Naphthalene sulfonamide isothiocyanate bifunctional micromolecules as well as preparation method and application thereof | 宁夏医科大学 | 2021-08-17 | — | — | CN | claimed |
| JP-2007505922-A | — | — | 2007-03-15 | — | — | JP | claimed |
| US-20060211728-A1 | Thalidomide analogs | P2D INC. | 2006-09-21 | — | — | US | claimed |
| EP-1663223-A2 | THALIDOMIDE ANALOGS AS TNF-ALPHA MODULATORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005028436-A2 | THALIDOMIDE ANALOGS AS TNF-ALPHA MODULATORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-03-31 | — | — | WO | claimed |
| US-4808696-A | FROM DIANHYDRIDE AND/OR DIIMIDES AND ALKALI METAL SULFIDE | GENERAL ELECTRIC COMPANY (US) | 1989-02-28 | — | — | US | claimed |
| EP-0293693-A2 | Method for making organobis(Thioether)s, and products obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1988-12-07 | — | — | EP | claimed |
| WO-2024094566-A1 | INDACENE AND AZAINDACENE COMPOUNDS AND HIGHER HOMOLOGUES AND THE USE THEREOF | Credoxys GmbH (DE) | 2024-05-10 | — | — | WO | disclosed |
| CN-117551023-A | Preparation method and application of N-thio-phenyl phthalimide compound | 太原理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117551023-A | Preparation method and application of N-thio-phenyl phthalimide compound | 太原理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117447370-A | Preparation method of aggregation-induced emission material tetraaryl divinyl sulfide | 山西蓬勃健康科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-113754621-B | Synthesis method of 2,3',3,4' -diphenyl sulfone tetracarboxylic dianhydride | 常州市阳光药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-0293693-A2 | Method for making organobis(Thioether)s, and products obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |
| US-4729986-A | AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0251086-A2 | Antifungal carbinols | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4409018-A | HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0041256-A1 | Hexahydroisoindol derivatives, process for producing said compounds and herbicides containing said compounds | Takeda Chemical Industries, Ltd. (JP) | 1981-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211728-A1 | Thalidomide analogs | TNF, TNFRSF1A, PGF | POLB 2461/4885CDC25B 200/4885EHMT2 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.