Sugi Predict

Sugi Predict / Compounds / SCHEMBL1771

SCHEMBL1771

SCHEMBL1771

O=C1c2ccccc2C(=O)N1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.48
▸ CASP3 P42574 1/20 0.46
▸ KMT2A Q03164 4/20 0.45
▸ MEN1 O00255 3/20 0.45
▸ CDC25B P30305 2/20 0.45
▸ EHMT2 Q96KQ7 2/20 0.44
▸ EHMT1 Q9H9B1 2/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ MAOA P21397 2/20 0.43
▸ CA12 O43570 1/20 0.43
▸ CA9 Q16790 1/20 0.43
▸ GLS O94925 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ CES2 O00748 1/20 0.43
▸ APAF1 O14727 1/20 0.43
▸ TERT O14746 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ PLIN1 O60240 1/20 0.43
▸ TDP2 O95551 1/20 0.43
▸ S1PR4 O95977 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385866 1.00 POLB (0.48) POLBCASP3KMT2AMEN1CDC25B
SCHEMBL30572531 0.97 POLB (0.46) POLBCASP3KMT2AMEN1CDC25B
SCHEMBL6734026 0.78 ERCC1 (0.63) KMT2AMEN1CYP1A2KDM4ECES2
SCHEMBL7686013 0.76 KMT2A (0.53) POLBKMT2AMEN1MAOAKDM4E
SCHEMBL454827 0.75 POLB (0.67) POLBCASP3KMT2AMEN1CDC25B
SCHEMBL3681059 0.74 CA2 (0.44) POLBKMT2AMEN1CA12CA9
SCHEMBL2022462 0.73 POLB (0.64) POLBCASP3KMT2AMEN1CDC25B
SCHEMBL134793 0.73 POLB (0.56) POLBCASP3KMT2AMEN1CDC25B
SCHEMBL28160078 0.73 POLB (0.64) POLBCASP3KMT2AMEN1CDC25B
SCHEMBL31634050 0.72 CES1 (0.57) MAOACES2BCHECES1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1789 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076261-A Anti-aging polyimide gas separation membrane and preparation method and application thereof — 2026-05-26 — — CN claimed
CN-116496265-B Synthesis method of posaconazole halocyclization intermediate 浙江海翔药业股份有限公司 2026-05-15 — — CN claimed
CN-119019675-B Allyl polyphenyl ether resin and preparation method thereof, flexible low-dielectric material and preparation method thereof 北京化工大学 2025-06-10 — — CN claimed
US-12279526-B2 Disubstituted fluoroaryloxybenzoheterodiazole compounds ENI S.P.A. (IT) 2025-04-15 — — US claimed
WO-2025059054-A1 PROCESS FOR PREPARING (2S,4S,4'S,6S)-2-METHYL-6-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-2',-(TRIELUOROMETHYL)-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO [2,3-C] PYRAN] -4'-OL VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-03-20 — — WO claimed
CN-119463159-A Silanized polyphenyl ether resin and preparation method thereof, high-temperature-resistant low-dielectric material and preparation method thereof 北京化工大学 2025-02-18 — — CN claimed
US-20250011297-A1 PROCESS AND INTERMEDIATES FOR PREPARATION OF ISOFETAMID ADAMA MAKHTESHIM LTD. (IL) 2025-01-09 — — US claimed
CN-119019675-A Allyl polyphenyl ether resin and preparation method thereof, flexible low-dielectric material and preparation method thereof 北京化工大学 2024-11-26 — — CN claimed
CN-118878540-A Preparation method and application of imidazo [1,2-a ] pyrazine compound 广州医科大学 2024-11-01 — — CN claimed
US-20240360125-A9 2-SUBSTITUTED BICYCLO[1.1.1]PENTANES THE TRUSTEES OF PRINCETON UNIVERSITY 2024-10-31 — — US claimed
US-4251450-A REACTING AMIDE WITH N-HALO IMIDE TO FORM N-HALO AMIDE, STEROID N-HALO AMIDES HENKEL CORPORATION (US) 1981-02-17 — — US claimed
US-4237215-A DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 — — US claimed
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 — — US claimed
US-4113591-A BROMINATION IN PRESENCE OF ULTRAVIOLET RADIATION, VISIBLE LIGHT, OR GAMMA RAYS GLAXO LABORATORIES LIMITED (GB) 1978-09-12 — — US claimed
US-4068072-A CHLORINATION OR BROMINATION, SOLVOLYSIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1978-01-10 — — US claimed
US-4051320-A PROCESS FOR PREPARING ALKOXYLATED DERIVATIVES OF CEPHALOSPORIN COMPOUNDS SANKYO COMPANY LIMITED (JA) 1977-09-27 — — US claimed
US-4051126-A HALOGENATION, ALKOXYLATION YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1977-09-27 — — US claimed
US-4032348-A METHOD FOR FORMING PHASE HOLOGRAMS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 — — US claimed
US-3948659-A BLEACHING FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 — — US claimed
US-3932352-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-01-13 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12279526-B2 Disubstituted fluoroaryloxybenzoheterodiazole compounds LSS, DDC, HLCS POLB 2311/4885CASP3 3883/4885KMT2A 1456/4885
US-20240360125-A9 2-SUBSTITUTED BICYCLO[1.1.1]PENTANES CYP1B1, BMP2, CCR1 POLB 236/4885CASP3 1817/4885KMT2A 4173/4885
US-20250011297-A1 PROCESS AND INTERMEDIATES FOR PREPARATION OF ISOFETAMID IDH2, FH, SDHA POLB 622/4885CASP3 3344/4885KMT2A 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.