SCHEMBL4413569

SCHEMBL4413569

CCC(=O)Nc1cncc(NC(=O)CC)n1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 16/20 0.45
ADORA1 P30542 11/20 0.45
ADORA2A P29274 10/20 0.45
ADORA2B P29275 7/20 0.45
HSD17B10 Q99714 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19706738 0.89 NPC1 (0.44) ADORA3ADORA1ADORA2AADORA2BSMN1; SMN2
SCHEMBL23368466 0.87 ADORA3 (0.40) ADORA3ADORA1ADORA2AADORA2BHSD17B10
SCHEMBL19706567 0.87 ADORA3 (0.44) ADORA3ADORA1ADORA2AADORA2BHSD17B10
SCHEMBL19151182 0.84 ADORA3 (0.50) ADORA3ADORA1ADORA2AADORA2BHSD17B10
SCHEMBL17778400 0.84 ADORA3 (0.38) ADORA3ADORA1ADORA2AADORA2BHSD17B10
SCHEMBL17778558 0.81 CHEK1 (0.40) ADORA3ADORA1ADORA2AADORA2BHSD17B10
SCHEMBL4551457 0.79 SMN1; SMN2 (0.65) ADORA3ADORA1ADORA2AADORA2BSMN1; SMN2
SCHEMBL1722219 0.79 RAB9A (0.55) SMN1; SMN2KDM4EMAPTNPC1TP53
SCHEMBL17776976 0.78 CHEK1 (0.39) ADORA3ADORA1ADORA2AADORA2BSMN1; SMN2
SCHEMBL4552599 0.78 POLB (0.55) ADORA3ADORA1ADORA2AADORA2BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed