SCHEMBL4551457

SCHEMBL4551457

CCC(=O)Nc1cccc(NC(=O)CC)n1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.65
RAB9A P51151 6/20 0.56
NPC1 O15118 4/20 0.56
POLB P06746 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
HPGD P15428 1/20 0.55
ADORA3 P0DMS8 6/20 0.53
ADORA1 P30542 6/20 0.53
ADORA2A P29274 5/20 0.53
ADORA2B P29275 3/20 0.53
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
NR4A1 P22736 1/20 0.50
MAPK8 P45983 1/20 0.49
GAA P10253 1/20 0.49
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8240316 0.89 RAB9A (0.71) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL19151419 0.89 SMN1; SMN2 (0.53) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL30071274 0.87 SMN1; SMN2 (0.51) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL6361201 0.87 CHRNB2 (0.53) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL16899020 0.87 XIAP (0.59) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL16899029 0.87 KMT2A (0.75) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL14413884 0.86 KDM4E (0.68) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL19151350 0.84 RAB9A (0.51) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL19151095 0.84 RAB9A (0.51) SMN1; SMN2RAB9ANPC1POLBTDP1
SCHEMBL25832634 0.84 SMN1; SMN2 (0.57) SMN1; SMN2RAB9ANPC1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10464929-B2 Organic molecules for terahertz tagging applications COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-11-05 US claimed
EP-3094621-B1 USE OF N-(PYRIDIN-2-YL)-AMIDE DERIVATIVES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL SCIENT IND RES (IN) 2019-06-19 EP claimed
EP-3094621-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS Council of Scientific & Industrial Research (IN) 2016-11-23 EP claimed
US-20160335827-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-17 US claimed
WO-2015104722-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-16 WO claimed
EP-3392240-B1 USE OF N-(PYRIDIN-2-YL)-AMIDE AND PHENYL-UREA DERIVATIVES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL SCIENT IND RES (IN) 2020-06-03 EP disclosed
EP-3392240-B1 USE OF N-(PYRIDIN-2-YL)-AMIDE AND PHENYL-UREA DERIVATIVES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL SCIENT IND RES (IN) 2020-06-03 EP disclosed
US-10464929-B2 Organic molecules for terahertz tagging applications COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-11-05 US disclosed
US-10464929-B2 Organic molecules for terahertz tagging applications COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-11-05 US disclosed
EP-3094621-B1 USE OF N-(PYRIDIN-2-YL)-AMIDE DERIVATIVES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL SCIENT IND RES (IN) 2019-06-19 EP disclosed
EP-3392240-A1 USE OF N-(PYRIDIN-2-YL)-AMIDE AND PHENYL-UREA DERIVATIVES FOR TERAHERTZ TAGGING APPLICATIONS Council Of Scientific & Industrial Research (IN) 2018-10-24 EP disclosed
EP-3094621-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS Council of Scientific & Industrial Research (IN) 2016-11-23 EP disclosed
US-20160335827-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-17 US disclosed
US-20160335827-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-17 US disclosed
US-20160335827-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-17 US disclosed
WO-2015104722-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-16 WO disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160335827-A1 ORGANIC MOLECULES FOR TERAHERTZ TAGGING APPLICATIONS WIZ, CRYZ, NAA15 SMN1; SMN2 4767/4885RAB9A 4203/4885NPC1 4342/4885
US-10464929-B2 Organic molecules for terahertz tagging applications WIZ, CRYZ, NAA15 SMN1; SMN2 4767/4885RAB9A 4203/4885NPC1 4342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.