Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140950 | 0.83 | EGFR (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL7859850 | 0.81 | KEAP1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL31115079 | 0.80 | MAPT (0.49) | CYP1A2CYP3A4CYP2D6CYP2C9HIF1A | |
| SCHEMBL28242000 | 0.77 | MAPT (0.44) | CYP3A4CYP2C19ALDH1A1GAAMAPT | |
| SCHEMBL23804836 | 0.75 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL2961433 | 0.73 | TDP1 (0.37) | CYP1A2CYP2C19CYP2C9ALDH1A1GAA | |
| SCHEMBL971316 | 0.73 | HTR2A (0.37) | CYP1A2CYP3A4CYP2D6ALDH1A1GAA | |
| SCHEMBL5880775 | 0.72 | HSD11B1 (0.41) | CYP2C19ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL3147406 | 0.72 | KDM4E (0.39) | CYP2C19ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL10370767 | 0.72 | KDM4E (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638565-B2 | Polyacetal resin composition | POLYPLASTICS CO., LTD. (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20070054998-A1 | Polyacetal resin composition | POLYPLASTICS CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1686156-A1 | POLYACETAL RESIN COMPOSITION | Polyplastics Co., Ltd. (JP) | 2006-08-02 | — | — | EP | disclosed |