Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.58 |
| ▸ | THRA | P10827 | 8/20 | 0.58 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | RXRA | P19793 | 3/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGAV | P06756 | 1/20 | 0.58 |
| ▸ | PCNA | P12004 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271628 | 0.78 | TPMT (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| Tetrac SCHEMBL365951 | 0.77 | THRB (1.00) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL12837302 | 0.72 | THRB (0.89) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL12837223 | 0.70 | THRB (0.83) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL14240614 | 0.68 | THRB (0.79) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL9522943 | 0.68 | THRB (0.64) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL1525946 | 0.67 | THRB (0.73) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL13949709 | 0.67 | THRB (0.77) | THRBTHRAPPARGRXRAITGB3 | |
| Tiratricol SCHEMBL30161572 | 0.66 | THRB (1.00) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL19696744 | 0.66 | THRB (0.76) | THRBTHRAPPARGRXRAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | claimed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | claimed |