SCHEMBL4271628

SCHEMBL4271628

O=C(Nc1c(I)ccc(C(=O)O)c1I)c1cc(I)c(I)c(I)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TPMT P51580 1/20 0.47
▸ KMT2A Q03164 8/20 0.41
▸ MEN1 O00255 7/20 0.41
▸ MAPT P10636 5/20 0.41
▸ TDP1 Q9NUW8 5/20 0.41
▸ PKM P14618 4/20 0.41
▸ GRIK1 P39086 1/20 0.41
▸ ACLY P53396 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ HTT P42858 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ AKR1C4 P17516 2/20 0.37
▸ AKR1C3 P42330 2/20 0.37
▸ AKR1C2 P52895 2/20 0.37
▸ AKR1C1 Q04828 2/20 0.37
▸ ABL1 P00519 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ RIN1 Q13671 1/20 0.37
▸ PTPN11 Q06124 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14275457 0.78 TPMT (0.67) TPMTKMT2AMEN1MAPTTDP1
Tetrac SCHEMBL4413711 0.78 THRB (0.58) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL14264013 0.70 TPMT (0.44) TPMTKMT2AMEN1MAPTALDH1A1
SCHEMBL28441204 0.69 KMT2A (0.43) KMT2AMEN1MAPTTDP1ACLY
SCHEMBL28219462 0.67 CYP1A2 (0.48) TPMTMAPTGRIK1ALDH1A1TSHR
SCHEMBL625273 0.67 CYP1A2 (0.48) TPMTMAPTGRIK1ALDH1A1TSHR
SCHEMBL122324 0.67 TPMT (1.00) TPMTMAPTTDP1PKMALDH1A1
SCHEMBL3808402 0.66 CYP1A2 (0.58) TPMTMAPTALDH1A1AKR1C3TSHR
SCHEMBL16674862 0.66 TSHR (0.42) TPMTKMT2AMEN1MAPTTDP1
Hydrochloric Acid SCHEMBL3280994 0.66 CYP1A2 (0.46) TPMTKMT2AMEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080064848-A1 Radiopaque amide polymers and medical devices formed thereof BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-13 — — US claimed
CN-222466879-U Ureteroscope on X-ray development scale 佛山复星禅诚医院有限公司 2025-02-14 — — CN disclosed
EP-3873547-B1 A RADIOPAQUE POLYMERIC LIQUID EMBOLIC SYSTEM SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECH (IN) 2024-08-07 — — EP disclosed
US-11986571-B2 Radiopaque polymeric liquid embolic system SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY (IN) 2024-05-21 — — US disclosed
US-8507639-B2 Polyamide block polymers containing iodoarylcarboxyl pendant groups and modified poly(meth)acrylamide; coupling; for tracking movement of a catheter through the body or inflation of balloon at site BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-08-13 — — US disclosed
EP-2066362-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF Boston Scientific Limited (BB) 2009-06-10 — — EP disclosed
WO-2008033198-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF BOSTON SCIENTIFIC LIMITED (BB) 2008-03-20 — — WO disclosed
US-20080064848-A1 Radiopaque amide polymers and medical devices formed thereof BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-13 — — US disclosed
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