Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15278730 | 0.85 | TRPA1 (0.39) | ESR1ESR2TRPA1LMNATSHR | |
| SCHEMBL955278 | 0.83 | TRPA1 (0.48) | ESR1ESR2TRPA1TSHRMAP2K1 | |
| Hydrochloric Acid SCHEMBL5299628 | 0.81 | TRPA1 (0.46) | ESR1ESR2TRPA1TSHRMAP2K1 | |
| SCHEMBL1344286 | 0.80 | ESR1 (0.68) | ESR1ESR2TRPA1LMNATSHR | |
| SCHEMBL2119593 | 0.80 | LMNA (0.42) | TRPA1LMNAMIFTAAR1MEN1 | |
| SCHEMBL19450022 | 0.79 | TRPA1 (0.47) | ESR1ESR2TRPA1LMNATSHR | |
| SCHEMBL19450024 | 0.79 | TRPA1 (0.47) | ESR1ESR2TRPA1LMNATSHR | |
| SCHEMBL19450023 | 0.79 | TRPA1 (0.47) | ESR1ESR2TRPA1LMNATSHR | |
| SCHEMBL11546302 | 0.79 | UGT2B7 (0.47) | ESR1ESR2TSHRMEN1KMT2A | |
| SCHEMBL7711210 | 0.78 | ESR1 (0.44) | ESR1ESR2TRPA1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8852565-B2 | Odour-reducing substances | SYMRISE AG (DE) | 2014-10-07 | — | — | US | claimed |
| WO-2023179870-A1 | ETHYL 4-OXOPENTANOATE FOR REDUCING ODORS | SYMRISE AG (DE) | 2023-09-28 | — | — | WO | disclosed |
| US-9102899-B2 | Organic compounds | GIVAUDAN SA (CH) | 2015-08-11 | — | — | US | disclosed |
| US-9102899-B2 | Organic compounds | GIVAUDAN SA (CH) | 2015-08-11 | — | — | US | disclosed |
| EP-2133102-B1 | Odor reducers | SYMRISE AG (DE) | 2014-12-03 | — | — | EP | disclosed |
| EP-2133102-A1 | Odor reducers | Symrise GmbH & Co. KG (DE) | 2009-12-16 | — | — | EP | disclosed |
| US-20080306170-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | disclosed |
| US-20080306170-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1818326-A1 | Nitrogen-containing heterocyclic compounds and pharmaceutical composition containing the compounds | Eisai R&D Management Co., Ltd. (JP) | 2007-08-15 | — | — | EP | disclosed |
| US-20060084658-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-04-20 | — | — | US | disclosed |
| US-6906072-B1 | Piperazine compound and pharmaceutical composition containing the compound | EISAI CO., LTD. (JP) | 2005-06-14 | — | — | US | disclosed |
| CN-1205185-C | Nitrogen-containing cyclic compound and pharmaceutical composition containing the same | EISAI CO LTD (JP) | 2005-06-08 | — | — | CN | disclosed |
| US-20040220193-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | EISAI CO., LTD. | 2004-11-04 | — | — | US | disclosed |
| CN-1395562-A | Nitrogenous cyclic compounds and pharmaceutical compositions containing the same | EISAI CO LTD (JP) | 2003-02-05 | — | — | CN | disclosed |
| EP-1254895-A1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306170-A1 | Organic Compounds | PNN, TRPA1, PAOX | ESR1 1971/4885ESR2 2304/4885TRPA1 2/4885 |
| US-20040220193-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | CACNA1D, CACNA1B, CACNA1E | ESR1 1667/4885ESR2 1095/4885TRPA1 93/4885 |
| US-20060084658-A1 | Nitrogen-containing cyclic compound and pharmaceutical composition containing the compound | CACNA1B, CACNA1E, CACNA1D | ESR1 1030/4885ESR2 1304/4885TRPA1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.