Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427903 | 0.88 | KHK (0.35) | KHKNR3C2 | |
| SCHEMBL4417848 | 0.81 | KHK (0.38) | KHK | |
| SCHEMBL4423364 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL733068 | 0.78 | ACACB (0.43) | — | |
| SCHEMBL4416831 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL3857043 | 0.76 | NPSR1 (0.31) | — | |
| SCHEMBL3855718 | 0.76 | PDE4A (0.35) | — | |
| SCHEMBL4414233 | 0.76 | HPGD (0.32) | — | |
| SCHEMBL4411155 | 0.75 | SCN9A (0.37) | — | |
| SCHEMBL4266728 | 0.75 | OPRD1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120569-A2 | SPIROCHROMANON DERIVATIVES | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008088692-A2 | SPIROCHROMANON DERIVATIVES | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | claimed |