SCHEMBL4414093

SCHEMBL4414093

CC1(C)C=CCC12C=CC(=O)CC2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.31
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7511344 0.71 ALOX5 (0.35) CYP19A1ALOX5
SCHEMBL17634056 0.68 ALOX5 (0.35) ALOX5
SCHEMBL17627600 0.67 HSD11B1 (0.30)
SCHEMBL4409815 0.66 ALDH1A1 (0.34) ALOX5
SCHEMBL33232 0.66 ALDH1A1 (0.39) CYP19A1
SCHEMBL24483574 0.66
SCHEMBL12687982 0.66
SCHEMBL31618858 0.63 ALDH1A1 (0.36) ALOX5
SCHEMBL9541235 0.63 ALDH1A1 (0.41) ALOX5
SCHEMBL3047562 0.63 ALOX5 (0.33) CYP19A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2137127-A2 NOVEL METHODS FOR PRODUCTION OF 5-EPI- BETA-VETIVONE, 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-2,6-DIEN-8-ONE, AND 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-1,6-DIEN-8-ONE Allylix, Inc. (US) 2009-12-30 EP disclosed
WO-2008116056-A2 NOVEL METHODS FOR PRODUCTION OF 5-EPI-β-VETIVONE, 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-2,6-DIEN-8-ONE, AND 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-1,6-DIEN-8-ONE ALLYLIX, INC. (US) 2008-09-25 WO disclosed