Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755706 | 0.92 | — | — | |
| SCHEMBL28788170 | 0.82 | LMNA (0.55) | LMNANFKB1TSHRPMP22GSTK1 | |
| SCHEMBL27814651 | 0.82 | LMNA (0.55) | LMNANFKB1TSHRPMP22GSTK1 | |
| SCHEMBL3643415 | 0.80 | — | — | |
| SCHEMBL11536608 | 0.80 | LCK (0.59) | LMNANFKB1TSHRPMP22GSTK1 | |
| SCHEMBL3059051 | 0.80 | LMNA (0.52) | LMNANFKB1TSHRPMP22GSTK1 | |
| SCHEMBL30945134 | 0.80 | LMNA (0.52) | LMNANFKB1TSHRPMP22GSTK1 | |
| SCHEMBL4655081 | 0.80 | LMNA (0.52) | LMNANFKB1TSHRPMP22GSTK1 | |
| SCHEMBL27528132 | 0.79 | LTA4H (0.33) | LMNAGSTK1ENPEPFFAR4FFAR1 | |
| SCHEMBL23829849 | 0.78 | TSHR (0.55) | LMNANFKB1TSHRPMP22GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485742-B2 | Non-glycosidic and non-peptidic inhibitors of selectin, and the use thereof | Johannes Gutenberg-Universität Mainz (DE) | 2009-02-03 | — | — | US | disclosed |
| US-20070276036-A1 | Non-Glycosidic and Non-Peptidic Select Inhibitors, and the Use Thereof | JOHANNES GUTENBERG-UNIVERSITAT MAINZ (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276036-A1 | Non-Glycosidic and Non-Peptidic Select Inhibitors, and the Use Thereof | VCAM1, ICAM1, SELPLG | LMNA 3043/4885NFKB1 1495/4885TSHR 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.