Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14310497 | 0.89 | CES1 (0.43) | TPMTCES1ACHEHCAR1GAA | |
| SCHEMBL980627 | 0.86 | CES2 (0.50) | CES1ACHEGAAMEN1PLA2G1B | |
| SCHEMBL738536 | 0.84 | TPMT (0.50) | TPMTHCAR1GAAMEN1PLA2G1B | |
| SCHEMBL18536573 | 0.82 | TPMT (0.48) | TPMTHCAR1GAAMEN1PLA2G1B | |
| SCHEMBL19136413 | 0.82 | TPMT (0.48) | TPMTACHEHCAR1GAAMEN1 | |
| SCHEMBL18536519 | 0.81 | CES1 (0.37) | TPMTCES1ACHEHCAR1GAA | |
| SCHEMBL113432 | 0.79 | CES1 (0.46) | CES1ACHECYP3A4TSHRMLYCD | |
| SCHEMBL111125 | 0.79 | ACHE (0.58) | CES1ACHEGAACYP2C19RAB9A | |
| SCHEMBL29791495 | 0.79 | ACHE (0.58) | CES1ACHEGAACYP2C19RAB9A | |
| SCHEMBL28482954 | 0.78 | TPMT (0.54) | TPMTHCAR1TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677605-B | Preparation method of S-configuration-fluorine Lei Lana | 瑞普（天津）生物药业有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117510428-A | Preparation process method of isoxazoline substituted benzamide compound | 中国农业大学 | 2024-02-06 | — | — | CN | claimed |
| CN-113024390-B | Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone derivative | 台州臻挚生物科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-116535298-B | Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone | 研峰科技(北京)有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-116535298-A | Synthesis method of 3',5' -dichloro-2, 2-trifluoro acetophenone | 研峰科技(北京)有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-113759052-B | Method for detecting related substances in fluorine Lei Lana initiator | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113899833-B | Determination of 1, 3-dichloro-5- (1-trifluoromethyl-vinyl) benzene by gas chromatography | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-112028752-B | Synthetic method of 3',5' -dichloro-2, 2-trifluoroacetophenone | 台州臻挚生物科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115677605-A | Preparation method of S-shaped fluorine Lei Lana | 瑞普（天津）生物药业有限公司 | 2023-02-03 | — | — | CN | claimed |
| WO-2022174524-A1 | METHOD FOR SYNTHESIZING 3',5'-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE DERIVATIVE | 台州臻挚生物科技有限公司 | 2022-08-25 | — | — | WO | claimed |
| CN-112110803-B | Preparation method of 3',5' -dichloro-2, 2, 2-trifluoro acetophenone | 台州臻挚生物科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114315748-A | Synthesis method of flurarana | 江苏天和制药有限公司 | 2022-04-12 | — | — | CN | claimed |
| WO-2022061917-A1 | SYNTHESIS METHOD FOR 3',5'-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE | 台州臻挚生物科技有限公司 | 2022-03-31 | — | — | WO | claimed |
| WO-2022061920-A1 | METHOD FOR PREPARING 3',5'-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE | 台州臻挚生物科技有限公司 | 2022-03-31 | — | — | WO | claimed |
| CN-113899833-A | Determination of 1, 3-dichloro-5- (1-trifluoromethyl-vinyl) benzene by gas chromatography | 丽珠集团新北江制药股份有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113759052-A | Method for detecting related substances in frataxin initiator | 丽珠集团新北江制药股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| WO-2021240331-A1 | PROCESS FOR THE PREPARATION OF 3,5-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE | HIKAL LIMITED (IN) | 2021-12-02 | — | — | WO | claimed |
| CN-113024390-A | Synthetic method of 3',5' -dichloro-2, 2, 2-trifluoro acetophenone derivative | 台州臻挚生物科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-112110803-A | Preparation method of 3',5' -dichloro-2, 2, 2-trifluoro acetophenone | 台州臻挚生物科技有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-112028752-A | Synthetic method of 3',5' -dichloro-2, 2, 2-trifluoro acetophenone | 台州臻挚生物科技有限公司 | 2020-12-04 | — | — | CN | claimed |