Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841476 | 0.83 | LMNA (0.39) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL4760454 | 0.82 | CYP3A4 (0.42) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL21195120 | 0.81 | TRPA1 (0.39) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL23226978 | 0.80 | CYP3A4 (0.52) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL573757 | 0.77 | TYR (0.41) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL20285910 | 0.77 | LMNA (0.33) | LMNACYP3A4ALDH1A1TRPA1PTGS1 | |
| SCHEMBL1970931 | 0.77 | TRPA1 (0.45) | LMNATYRALDH1A1TSHRTRPA1 | |
| SCHEMBL16132833 | 0.77 | CYP3A4 (0.38) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL24451054 | 0.76 | CYP3A4 (0.41) | LMNACYP3A4MAPK1TYRALDH1A1 | |
| SCHEMBL20884656 | 0.76 | CYP3A4 (0.52) | LMNACYP3A4MAPK1TYRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4683345-A | CONDENSATION, SULFURIC ACID CATALYST | Nouvel, Colette (FR) | 1987-07-28 | — | — | US | claimed |
| US-4154968-A | Bactericidic and fungicidic chloromethylisopropyphenols | CHRYSA (FR) | 1979-05-15 | — | — | US | claimed |
| US-20230373952-A1 | LACTAM COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-11-23 | — | — | US | disclosed |
| US-20230373952-A1 | LACTAM COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-11-23 | — | — | US | disclosed |
| US-20230203063-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20220119409-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. | 2022-04-21 | — | — | US | disclosed |
| WO-2021127404-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-109942427-A | A kind of monoterpene phenol derivatives and its synthetic method and the application in pesticide | 云南农业大学 | 2019-06-28 | — | — | CN | disclosed |
| WO-2014001057-A1 | ANTIMICROBIAL COMPOSITION | UNILEVER N.V. (NL) | 2014-01-03 | — | — | WO | disclosed |
| EP-2136648-A1 | CENTER-FILLED CHEWING GUM PRODUCT FOR DENTAL CARE | Gumlink A/S (DK) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008122286-A1 | CENTER-FILLED CHEWING GUM PRODUCT FOR DENTAL CARE | GUMLINK A/S (DK) | 2008-10-16 | — | — | WO | disclosed |
| US-4683345-A | CONDENSATION, SULFURIC ACID CATALYST | Nouvel, Colette (FR) | 1987-07-28 | — | — | US | disclosed |
| US-4154968-A | Bactericidic and fungicidic chloromethylisopropyphenols | CHRYSA (FR) | 1979-05-15 | — | — | US | disclosed |
| US-4154968-A | Bactericidic and fungicidic chloromethylisopropyphenols | CHRYSA (FR) | 1979-05-15 | — | — | US | disclosed |
| US-4098828-A | BACTERICIDIC AND FUNGICIDIC CHLOROMETHYLISOPROPYLPHENOLS | CHRYSA (FR) | 1978-07-04 | — | — | US | disclosed |
| US-4098828-A | BACTERICIDIC AND FUNGICIDIC CHLOROMETHYLISOPROPYLPHENOLS | CHRYSA (FR) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203063-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | TYMS, TYMP, DHFR | LMNA 3865/4885CYP3A4 45/4885MAPK1 2326/4885 |
| US-20220119409-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | DHFR, TYMS, TYMP | LMNA 3922/4885CYP3A4 39/4885MAPK1 2279/4885 |
| US-20230373952-A1 | LACTAM COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNK3, KCNA3, KCNJ2 | LMNA 2352/4885CYP3A4 927/4885MAPK1 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.