Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478810 | 0.77 | CRBN (0.36) | TSHRLMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL14746060 | 0.67 | NOS2 (0.35) | TSHRLMNATNKS2GAA | |
| SCHEMBL2359522 | 0.66 | LMNA (0.38) | TSHRLMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL2233981 | 0.64 | TSHR (0.37) | TSHRLMNATNKS2ALDH1A1HSD17B10 | |
| SCHEMBL20159058 | 0.63 | TSHR (0.36) | TSHRLMNATNKS2ALDH1A1HSD17B10 | |
| SCHEMBL14785765 | 0.62 | TNKS2 (0.53) | TSHRLMNATNKS2ALDH1A1HSD17B10 | |
| SCHEMBL19183043 | 0.60 | TNKS2 (0.42) | TSHRLMNATNKS2ALDH1A1HSD17B10 | |
| SCHEMBL261677 | 0.59 | LMNA (0.35) | TSHRLMNATNKS2ALDH1A1HSD17B10 | |
| SCHEMBL19568178 | 0.59 | TSHR (0.50) | TSHRLMNATNKS2ALDH1A1HSD17B10 | |
| SCHEMBL6557130 | 0.59 | TSHR (0.50) | TSHRLMNATNKS2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745870-B | Ondansetron intermediate of agar Synthesis method of tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118666733-A | Application of tetrahydrocarbazole micromolecule compounds in preparation of antiviral drugs and preparation method thereof | 中国人民解放军空军军医大学 | 2024-09-20 | — | — | CN | claimed |
| CN-115677559-B | One-step synthesis method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-114634442-B | Preparation method of tetrahydrocarbazolone compound | 内蒙古民族大学 | 2023-10-13 | — | — | CN | claimed |
| CN-115745870-A | Synthetic method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115677559-A | One-step synthesis method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114634442-A | Preparation method of tetrahydrocarbazolone compound | 内蒙古民族大学 | 2022-06-17 | — | — | CN | claimed |
| CN-110003187-B | Polyfluoroalkyl substituted benzofuran compound and preparation method thereof | 南京工业大学 | 2021-11-05 | — | — | CN | claimed |
| CN-107298640-B | Preparation method and application of methylene ketone compound | 曲阜师范大学 | 2020-08-04 | — | — | CN | claimed |
| CN-110105812-A | A kind of no ink ink-jet ink and its preparation method and application | 重庆理工大学 | 2019-08-09 | — | — | CN | claimed |
| EP-0934309-A1 | NEW PYRIDYL ALKANE ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | Klinge Pharma GmbH (DE) | 1999-08-11 | — | — | EP | claimed |
| EP-0923570-A1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | Klinge Pharma GmbH (DE) | 1999-06-23 | — | — | EP | claimed |
| EP-0912176-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | Klinge Pharma GmbH (DE) | 1999-05-06 | — | — | EP | claimed |
| WO-1997048397-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
| WO-1997048696-A1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
| WO-1997048695-A1 | NEW PYRIDYL ALKANE ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
| CN-1113913-A | Preparing method for 1,2,3,9-tetrahydro-9-methyl-3[(2-methyl-1H-imidazo-1-lyl)methyl]-4H-carbazole-4-ketone and its salts | QILU PHARMACEUTICAL FACTORY (CN) | 1995-12-27 | — | — | CN | claimed |
| US-5411968-A | 5-hydroxytryptamine antagonists | GLAXO GROUP LIMITED (GB) | 1995-05-02 | — | — | US | claimed |
| EP-0229444-A2 | Medicaments for the treatment of anxiety | GLAXO GROUP LIMITED (GB) | 1987-07-22 | — | — | EP | claimed |
| EP-0028270-A1 | Pyrazino-carbazoles, process for their preparation and pharmaceutical compositions containing them | CASSELLA Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | claimed |