Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437986 | 0.91 | DGAT1 (0.55) | DGAT1HPGD | |
| SCHEMBL440582 | 0.90 | DGAT1 (0.54) | DGAT1CYP2C19POLB | |
| SCHEMBL441311 | 0.90 | HPGD (0.55) | DGAT1HPGD | |
| SCHEMBL440637 | 0.88 | DGAT1 (0.53) | DGAT1HPGD | |
| SCHEMBL441098 | 0.87 | L3MBTL1 (0.55) | DGAT1HPGD | |
| SCHEMBL14305144 | 0.87 | DGAT1 (0.53) | DGAT1CYP2C19POLB | |
| SCHEMBL463713 | 0.87 | DGAT1 (0.60) | DGAT1TP53RXFP1 | |
| SCHEMBL441403 | 0.86 | DGAT1 (0.61) | DGAT1TP53RXFP1 | |
| SCHEMBL441402 | 0.86 | DGAT1 (0.61) | DGAT1TP53RXFP1 | |
| SCHEMBL462759 | 0.85 | DGAT1 (0.57) | DGAT1TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | DGAT1 2/4885HPGD 1034/4885TP53 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.