SCHEMBL4416045

SCHEMBL4416045

CC(=O)N(N=NCc1ccccc1)C(C)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.43
ALDH1A1 P00352 2/20 0.41
TSPO P30536 1/20 0.39
LMNA P02545 2/20 0.39
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
SCN2A Q99250 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
AKR1B1 P15121 1/20 0.38
PTGS1 P23219 2/20 0.36
ALOX5 P09917 1/20 0.36
PTGS2 P35354 1/20 0.36
ALPI P09923 1/20 0.36
PKM P14618 1/20 0.36
XIAP P98170 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butanedione SCHEMBL5315580 0.72 NOS2 (0.48) NOS2ALDH1A1LMNASCN2ACES2
SCHEMBL5313132 0.70 NOS2 (0.43) NOS2ALDH1A1LMNA
SCHEMBL4416043 0.70 UBE2N (0.40) NOS2ALDH1A1NPC1RAB9APTGS1
SCHEMBL1040588 0.70 NOS2 (0.50) NOS2ALDH1A1LMNACES2CES1
SCHEMBL19611522 0.70 ALDH1A1 (0.52) NOS2ALDH1A1
SCHEMBL15506263 0.70 ALDH1A1 (0.52) NOS2ALDH1A1
SCHEMBL17178869 0.70 ALDH1A1 (0.52) NOS2ALDH1A1
Acetic Acid SCHEMBL29114915 0.68 HDAC3 (0.46) NOS2ALDH1A1LMNASCN2ACES2
SCHEMBL12615939 0.68 ALDH1A1 (0.42) NOS2ALDH1A1TSPOLMNACRHBP
SCHEMBL7095730 0.67 NOS2 (0.57) NOS2ALDH1A1LMNASCN2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1537796-B1 Anti-microbial elastomeric flexible article, such as a glove, and manufacturing method CHOU BELLE L (US) 2009-12-30 EP claimed
CN-1636474-A Antibacterial elastic soft article and method of manufacture CHOU BELLE L (US) 2005-07-13 CN claimed
EP-1537796-A2 Anti-microbial elastomeric flexible article, such as a glove, and manufacturing method Chou, Belle L. (US) 2005-06-08 EP claimed
US-20050112180-A1 Antimicrobial elastomeric flexible article and manufacturing method SHEN WEI (USA) INC. 2005-05-26 US claimed
EP-1157708-A2 Anti-microbial surgical devices ETHICON, INC. (US) 2001-11-28 EP claimed
US-20210301428-A1 HIGH TENACITY FIBER AND MINERAL REINFORCED BLENDED YARNS Ansell Limited (AU) 2021-09-30 US disclosed
US-11047069-B2 High tenacity fiber and mineral reinforced blended yarns Ansell Limited (AU) 2021-06-29 US disclosed
CN-206109615-U High tenacity fibers, mineral reinforced blended yarns and composite yarns 安塞尔有限公司 2017-04-19 CN disclosed
EP-3063320-A1 HIGH TENACITY FIBER AND MINERAL REINFORCED BLENDED YARNS Ansell Limited (AU) 2016-09-07 EP disclosed
US-20150210037-A1 ABSORBENT, CUSHIONED, IMPERMEABLE, REVERSIBLE, NON-SLIP, NON-CURLING LAMINATE LINER KIT WITH CUTTING GUIDE TODD MARK (US) 2015-07-30 US disclosed
US-20150118425-A1 HIGH TENACITY FIBER AND MINERAL REINFORCED BLENDED YARNS Ansell Limited (AU) 2015-04-30 US disclosed
EP-1537796-B1 Anti-microbial elastomeric flexible article, such as a glove, and manufacturing method CHOU BELLE L (US) 2009-12-30 EP disclosed
EP-0433358-B1 TUBULAR ARTICLES SMITH & NEPHEW (GB) 1994-03-02 EP disclosed
US-5261421-A Microbiocides SMITH & NEPHEW PLC (GB) 1993-11-16 US disclosed
US-5180605-A 2,4,4'-Trichloro-2'-Hydroxyphenyl Ether Microbiocide SMITH & NEPHEW P.1.C. (GB) 1993-01-19 US disclosed
US-5091442-A TUBULAR ARTICLES SMITH AND NEPHEW PLC (GB) 1992-02-25 US disclosed
US-5031245-A Medical SMITH & NEPHEW PLC (GB) 1991-07-16 US disclosed
EP-0433358-A1 TUBULAR ARTICLES. SMITH & NEPHEW (GB) 1991-06-26 EP disclosed
WO-1990002573-A1 TUBULAR ARTICLES SMITH & NEPHEW PLC (GB) 1990-03-22 WO disclosed
EP-0350147-A2 Surgical gloves SMITH & NEPHEW INC. (US) 1990-01-10 EP disclosed