SCHEMBL4416245

SCHEMBL4416245

CC(C)(O)C(=O)c1ccc(OCCOC(=O)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
MAPT P10636 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
GAA P10253 2/20 0.38
PKM P14618 1/20 0.38
PPARG P37231 2/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 2/20 0.37
PARP10 Q53GL7 1/20 0.36
PPARA Q07869 1/20 0.36
HTT P42858 1/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4421158 0.95 CA1 (0.48) CA1CA2MAPTL3MBTL1GAA
SCHEMBL6047046 0.95 CA1 (0.48) CA1CA2MAPTL3MBTL1GAA
SCHEMBL6047039 0.95 CA1 (0.48) CA1CA2MAPTL3MBTL1GAA
SCHEMBL4415099 0.87 CA1 (0.41) CA1CA2MAPTL3MBTL1GAA
SCHEMBL14948937 0.85 MAPT (0.46) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL6047056 0.84 CA1 (0.36) CA1CA2MAPTL3MBTL1GAA
SCHEMBL19691441 0.83 MAPT (0.45) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL4425313 0.83 CA1 (0.47) CA1CA2MAPTL3MBTL1GAA
SCHEMBL13431266 0.81 MAPT (0.43) MAPTL3MBTL1GAAPKMRAB9A
SCHEMBL13583844 0.80 L3MBTL1 (0.49) MAPTL3MBTL1GAAPKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392779-B1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS CIBA HOLDING INC (CH) 2009-04-22 EP disclosed
EP-1392779-B1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS CIBA HOLDING INC (CH) 2009-04-22 EP disclosed
EP-1444271-A4 FLUORINATED OPTICAL POLYMER COMPOSITION DU PONT (US) 2005-03-02 EP disclosed
US-20040249081-A1 Halogenated optical polymer composition BLOMQUIST ROBERT M (US) 2004-12-09 US disclosed
US-6778753-B2 USED TO FABRICATE PLANAR OPTICAL WAVEGUIDES WITH LOW LOSS AND LOW BIREFRINGENCE E. I. DU PONT DE NEMOURS AND COMPANY 2004-08-17 US disclosed
EP-1444271-A1 FLUORINATED OPTICAL POLYMER COMPOSITION CORNING INCORPORATED (US) 2004-08-11 EP disclosed
US-20040067311-A1 Fluorinated-photoinitiators in dual cure resins CIBA SPECIALTY CHEMICALS CORP. 2004-04-08 US disclosed
EP-1392779-A1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS Ciba SC Holding AG (CH) 2004-03-03 EP disclosed
US-20030055120-A1 Halogenated optical polymer composition ENABLENCE TECHNOLOGIES USA INC. (CA) 2003-03-20 US disclosed
WO-2003011915-A1 FLUORINATED OPTICAL POLYMER COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-13 WO disclosed
WO-2002040602-A1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-05-23 WO disclosed