SCHEMBL14948937

SCHEMBL14948937

CC(C)(C)C(=O)OCCOc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.44
PPARA Q07869 1/20 0.43
ELANE P08246 3/20 0.42
PKM P14618 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 1/20 0.41
PARP10 Q53GL7 1/20 0.41
HTT P42858 1/20 0.39
POLB P06746 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19691441 0.90 MAPT (0.45) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL13431266 0.87 MAPT (0.43) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL20006396 0.86 MAPT (0.47) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL13583844 0.86 L3MBTL1 (0.49) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL22722488 0.86 L3MBTL1 (0.43) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL15828756 0.86 MAPT (0.45) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL12799434 0.85 HTT (0.56) MAPTL3MBTL1PKMGAARAB9A
SCHEMBL4416245 0.85 CA1 (0.43) MAPTL3MBTL1PPARAPKMGAA
SCHEMBL23515999 0.84 PKM (0.62) L3MBTL1PKMALDH1A1HTTPOLB
SCHEMBL13706551 0.84 RARB (0.44) MAPTL3MBTL1PPARAPKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851254-B2 Photoinitiators and curable compositions AGFA NV (BE) 2020-12-01 US disclosed
US-9314746-B2 Hydrophilic porous substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-04-19 US disclosed
US-8846203-B2 Method of making ligand functionalized substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-20140087445-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-03-27 US disclosed
US-20130118975-A1 HYDROPHILIC POROUS SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851254-B2 Photoinitiators and curable compositions FLOT1, VIM, FLNA MAPT 86/4885L3MBTL1 133/4885PPARA 3579/4885
US-20140087445-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES SPR, SELPLG, SIGLEC7 MAPT 4419/4885L3MBTL1 2708/4885PPARA 1426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.