Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.36 |
| ▸ | DRD4 | P21917 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrothiophene SCHEMBL23420978 | 0.86 | ALDH1A1 (0.39) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL15675859 | 0.83 | ESR1 (0.41) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL4423294 | 0.82 | KDM4E (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL7892253 | 0.81 | DRD2 (0.36) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL4427003 | 0.80 | HTT (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL4416580 | 0.80 | CXCR2 (0.32) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL4414225 | 0.76 | DRD2 (0.32) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL6851155 | 0.76 | MEN1 (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL6564931 | 0.75 | DRD2 (0.36) | DRD2DRD4DRD3DRD1DRD5 | |
| Tetrahydrothiophene SCHEMBL4423403 | 0.75 | TYMS (0.39) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270553-B1 | Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition | JSR CORP (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-1270553-A2 | Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition | JSR Corporation (JP) | 2003-01-02 | — | — | EP | disclosed |