Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrothiophene SCHEMBL4423294 | 0.90 | KDM4E (0.38) | CXCR2DRD2DRD1DRD4DRD5 | |
| Tetrahydrothiophene SCHEMBL4414225 | 0.86 | DRD2 (0.32) | DRD2DRD1DRD4DRD5DRD3 | |
| Tetrahydrothiophene SCHEMBL4423403 | 0.85 | TYMS (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| Tetrahydrothiophene SCHEMBL6564875 | 0.81 | GAA (0.34) | DRD2DRD1DRD4DRD5DRD3 | |
| Tetrahydrothiophene SCHEMBL23420978 | 0.80 | ALDH1A1 (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| Tetrahydrothiophene SCHEMBL4416481 | 0.80 | DRD2 (0.36) | CXCR2DRD2DRD1DRD4DRD5 | |
| Tetrahydrothiophene SCHEMBL15675859 | 0.79 | ESR1 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL2519048 | 0.76 | — | — | |
| SCHEMBL30003452 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL23271942 | 0.75 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270553-B1 | Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition | JSR CORP (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-1270553-A2 | Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition | JSR Corporation (JP) | 2003-01-02 | — | — | EP | disclosed |