Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231945 | 0.86 | F10 (0.55) | F10F2HRH3 | |
| SCHEMBL3368811 | 0.85 | F10 (0.51) | F10F2HRH3LRRK2 | |
| SCHEMBL1652749 | 0.81 | F10 (0.69) | F10F2 | |
| SCHEMBL1381845 | 0.81 | F10 (0.56) | F10F2HRH3 | |
| SCHEMBL1456377 | 0.80 | F10 (0.57) | F10F2 | |
| SCHEMBL4416019 | 0.79 | GRM5 (0.43) | F10GRM5 | |
| SCHEMBL3372792 | 0.78 | F10 (0.49) | F10F2HRH3 | |
| SCHEMBL3371161 | 0.78 | F10 (0.53) | F10F2 | |
| SCHEMBL4419134 | 0.77 | FLT3 (0.42) | F10 | |
| SCHEMBL6016992 | 0.75 | F10 (0.46) | F10F2HRH3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |