Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MYOC | Q99972 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128402 | 0.88 | LOXL2 (0.61) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL4739223 | 0.86 | LOXL2 (0.59) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| Bromide SCHEMBL2771283 | 0.86 | LOXL2 (0.59) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL27734100 | 0.86 | HSPB1 (0.56) | HSPB1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2000238 | 0.85 | HSPB1 (0.63) | HSPB1MAPK1ALDH1A1TSHRMAPT | |
| SCHEMBL19308585 | 0.84 | MAOB (0.68) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.84 | HSPB1 (0.79) | HSPB1MAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11689190 | 0.84 | HSPB1 (0.79) | HSPB1MAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9183872 | 0.84 | HSPB1 (0.79) | HSPB1MAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL2011179 | 0.84 | HSPB1 (0.79) | HSPB1MAPK1ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299354-B1 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-22 | — | — | EP | claimed |
| CN-119707816-A | Pyrazole hydrazide derivative containing diphenyl ether unit as well as preparation method and application thereof | 江苏海洋大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-110121519-B | Polyimide oligomer, composition, production method, and use thereof | 高新特殊工程塑料全球技术有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-110139889-B | Compositions and articles made from branched polyetherimides | 高新特殊工程塑料全球技术有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110062785-B | Composition of linear polyimide and branched polyimide | 高新特殊工程塑料全球技术有限公司 | 2021-10-29 | — | — | CN | disclosed |
| EP-1299354-B1 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-6743790-B2 | A UREA OR THIOUREA DERIVATIVES CONTAINING AMIDE GROUP USEFUL AS ANTICOAGULANTS AND ANTIINFLAMMATORY AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-01 | — | — | US | disclosed |
| EP-1299354-A2 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | Aventis Pharma Deutschland GmbH (DE) | 2003-04-09 | — | — | EP | disclosed |
| WO-2001094301-A2 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-13 | — | — | WO | disclosed |
| EP-1162194-A1 | Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use | Aventis Pharma Deutschland GmbH (DE) | 2001-12-12 | — | — | EP | disclosed |