Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | NCK1 | P16333 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908162 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP1A2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL28569226 | 0.85 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL858595 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP1A2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL30718860 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP1A2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL8404384 | 0.79 | CYP1A2 (0.54) | ALDH1A1CYP1A2KDM4EKMT2ANPSR1 | |
| SCHEMBL3661273 | 0.79 | KDM4E (0.48) | ALDH1A1CYP1A2KDM4ESMN1; SMN2MAPT | |
| SCHEMBL558609 | 0.76 | KDM4E (0.46) | ALDH1A1CYP1A2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL22449721 | 0.76 | CYP1A2 (0.50) | ALDH1A1CYP1A2KMT2ANPSR1MAPT | |
| SCHEMBL18630333 | 0.76 | CYP1A2 (0.50) | ALDH1A1CYP1A2KDM4EKMT2ANPSR1 | |
| SCHEMBL1633846 | 0.76 | BACE1 (0.47) | ALDH1A1CYP1A2KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |
| US-11548867-B2 | Amido compounds as AhR modulators | IDEA YA BIOSCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210115016-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-04-22 | — | — | US | disclosed |
| CN-109851617-A | Chemical entities, composition and method | 润新生物公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-108659005-B | Quinazoline derivatives as EGFR inhibitors | 南京明德新药研发股份有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-108640928-B | Quinazoline compounds as EGFR inhibitor | 南京明德新药研发股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108659005-A | Quinazoline derivatives as EGFR inhibitors | 南京明德新药研发股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108640928-A | Quinazoline compounds as EGFR inhibitor | 南京明德新药研发股份有限公司 | 2018-10-12 | — | — | CN | disclosed |
| EP-3365061-A1 | AMINOISOXAZOLINE COMPOUNDS AS AGONISTS OF ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTORS | Axovant Sciences GmbH (DE) | 2018-08-29 | — | — | EP | disclosed |
| CN-107759571-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-101356168-A | Quinazolines useful as modulators of voltage gated ion channels | VERTEX PHARMA (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-101068794-A | Quinazolines useful as modulators of ion channels | VERTEX PHARMA (US) | 2007-11-07 | — | — | CN | disclosed |
| US-7112590-B2 | Thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2006-09-26 | — | — | US | disclosed |
| US-20050165034-A1 | Novel heterocyclic derivatives of tripeptides and tripeptide mimetics; (+-)-2-[3-[(benzylsulfonyl)amino]-6-methyl-2-oxo-1 (2H)-pyridinyl]-N-[(4,5,6,7-tetrahydro-2H-indazole-5-yl]acetamide; anticoagulants | UNIVERSITY OF LJUBLJANA, FACULTY OF PHARMACY (SI) | 2005-07-28 | — | — | US | disclosed |
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | disclosed |
| EP-1451175-A1 | THROMBIN INHIBITORS | University of Ljubljana (SI) | 2004-09-01 | — | — | EP | disclosed |
| US-20030191139-A1 | Thrombin inhibitors | UNIVERSITY OF LJUBLJANA (SI) | 2003-10-09 | — | — | US | disclosed |
| WO-2003048155-A1 | THROMBIN INHIBITORS | UNIVERSITY OF LJUBLJANA (SI) | 2003-06-12 | — | — | WO | disclosed |
| EP-1287018-A2 | THROMBIN INHIBITORS | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001085760-A1 | THROMBIN INHIBITORS | LEK PHARMACEUTICAL & CHEMICAL CO. DD (SI) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191139-A1 | Thrombin inhibitors | TFPI, F2, SERPINC1 | ALDH1A1 2395/4885CYP1A2 353/4885KDM4E 3728/4885 |
| US-20050165034-A1 | Novel heterocyclic derivatives of tripeptides and tripeptide mimetics; (+-)-2-[3-[(benzylsulfonyl)amino]-6-methyl-2-oxo-1 (2H)-pyridinyl]-N-[(4,5,6,7-tetrahydro-2H-indazole-5-yl]acetamide; anticoagulants | SERPINC1, TFPI, SERPINE1 | ALDH1A1 2581/4885CYP1A2 1910/4885KDM4E 2920/4885 |
| US-20210115016-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | AHR, ARNT, RXRB | ALDH1A1 879/4885CYP1A2 62/4885KDM4E 880/4885 |
| US-11548867-B2 | Amido compounds as AhR modulators | AHR, ARNT, RXRB | ALDH1A1 879/4885CYP1A2 62/4885KDM4E 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.