SCHEMBL4416897

SCHEMBL4416897

CC(C)(c1ccc(OCC(=O)NN)cc1)c1ccc(OCC(=O)NN)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
KDM4E B2RXH2 4/20 0.52
LMNA P02545 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
OGG1 O15527 1/20 0.50
POLB P06746 2/20 0.48
GAA P10253 1/20 0.48
CYP2C19 P33261 1/20 0.48
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48
CASP3 P42574 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
HCAR2 Q8TDS4 1/20 0.47
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28491042 0.94 ALDH1A1 (0.64) ALDH1A1KDM4ELMNASMN1; SMN2POLB
SCHEMBL3252742 0.90 ALDH1A1 (0.71) ALDH1A1KDM4ELMNASMN1; SMN2POLB
SCHEMBL4422333 0.86 ALDH1A1 (0.73) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL15426837 0.84 ALDH1A1 (0.64) ALDH1A1KDM4ELMNASMN1; SMN2POLB
SCHEMBL4410656 0.84 ALDH1A1 (0.51) ALDH1A1KDM4ELMNASMN1; SMN2POLB
SCHEMBL21854420 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ELMNASMN1; SMN2OGG1
SCHEMBL11872758 0.81 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1GAA
SCHEMBL4412023 0.81 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAOGG1POLB
SCHEMBL5434584 0.81 ALDH1A1 (0.63) ALDH1A1KDM4ELMNASMN1; SMN2POLB
SCHEMBL15426830 0.80 ALDH1A1 (0.68) ALDH1A1KDM4ELMNASMN1; SMN2OGG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2684907-B1 RESIN, OPTICAL MATERIAL, AND OPTICAL DEVICE MITSUI CHEMICALS INC (JP) 2020-02-26 EP disclosed
US-9221949-B2 Resin, optical material, and optical device MITSUI CHEMICALS, INC. (JP) 2015-12-29 US disclosed
EP-2684907-A1 RESIN, OPTICAL MATERIAL, AND OPTICAL DEVICE Mitsui Chemicals, Inc. (JP) 2014-01-15 EP disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed