SCHEMBL4422333

SCHEMBL4422333

NNC(=O)COc1ccc(OCC(=O)NN)cc1

nearest known ligand 0.81

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.73
KDM4E B2RXH2 4/20 0.65
LMNA P02545 1/20 0.65
OGG1 O15527 2/20 0.58
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4413701 0.94 ALDH1A1 (0.67) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL15426830 0.94 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL4409512 0.90 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL5434584 0.90 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAMEN1KMT2A
SCHEMBL1303739 0.90 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL1713424 0.90 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAMEN1KMT2A
SCHEMBL11547674 0.90 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL11872758 0.90 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL2835832 0.90 ALDH1A1 (0.63) ALDH1A1KDM4ELMNAOGG1MEN1
SCHEMBL4412023 0.90 ALDH1A1 (0.68) ALDH1A1KDM4ELMNAOGG1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed