SCHEMBL4410656

SCHEMBL4410656

CC(C)(c1ccc(OCCC(=O)NN)cc1)c1ccc(OCCC(=O)NN)cc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.51
KDM4E B2RXH2 8/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
HTT P42858 1/20 0.51
POLB P06746 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
GPR35 Q9HC97 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4411547 0.87 MMP3 (0.54) ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL4416897 0.84 ALDH1A1 (0.71) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL4411549 0.82 CA1 (0.56) ALDH1A1HTTTDP1
SCHEMBL19043180 0.82 MAPT (0.61) ALDH1A1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL4412344 0.82 MMP3 (0.63) ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL4412300 0.82 MMP3 (0.50) ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL28491042 0.79 ALDH1A1 (0.64) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL4419519 0.79 LTA4H (0.50) KDM4ESMN1; SMN2
SCHEMBL6761507 0.79 ALDH1A1 (0.51) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL4414363 0.79 GAA (0.51) KDM4ESMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed