Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947302 | 0.84 | TRPA1 (0.41) | TRPA1ATMTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4417873 | 0.77 | — | — | |
| SCHEMBL4417231 | 0.76 | TRPA1 (0.33) | TRPA1ATM | |
| SCHEMBL4416027 | 0.76 | — | — | |
| SCHEMBL12477034 | 0.74 | TRPA1 (0.33) | TRPA1ATM | |
| SCHEMBL587377 | 0.72 | TRPA1 (0.38) | TRPA1ATMTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL15363723 | 0.72 | TRPA1 (0.38) | TRPA1ATMTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL29235984 | 0.71 | ATM (0.35) | TRPA1ATMTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8400131 | 0.71 | ALDH1A1 (0.38) | TRPA1ATMSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4417788 | 0.70 | CACNA2D1 (0.31) | TRPA1ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076521-B1 | SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES | UNIV ADAM MICKIEWICZ (PL) | 2012-12-26 | — | — | EP | disclosed |
| US-20090318726-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES | ADAM MICKIEWICZ UNIVERSITY (PL) | 2009-12-24 | — | — | US | disclosed |