SCHEMBL4417480

SCHEMBL4417480

CC(C)(c1ccc(C(O)CO)cc1)c1ccc(C(O)CO)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.44
TSHR P16473 3/20 0.44
ESR1 P03372 3/20 0.44
ESR2 Q92731 3/20 0.44
AR P10275 2/20 0.44
HPGD P15428 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HSD17B10 Q99714 1/20 0.44
LMNA P02545 2/20 0.40
ALDH1A1 P00352 2/20 0.39
KLF10 Q13118 1/20 0.38
RIPK1 Q13546 1/20 0.38
HIF1A Q16665 3/20 0.38
HTT P42858 1/20 0.38
TAAR1 Q96RJ0 2/20 0.35
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31376561 0.87 LMNA (0.51) CYP3A4TSHRSLC6A2SLC6A4HTR6
SCHEMBL23188717 0.87 LMNA (0.51) CYP3A4TSHRSLC6A2SLC6A4HTR6
SCHEMBL1629743 0.87 LMNA (0.51) CYP3A4TSHRSLC6A2SLC6A4HTR6
SCHEMBL548356 0.83 LMNA (0.56) CYP3A4TSHRESR1ESR2AR
SCHEMBL1100312 0.82 LMNA (0.47) CYP3A4TSHRSLC6A2SLC6A4HTR6
SCHEMBL17438169 0.81 TSHR (0.48) CYP3A4TSHRLMNAALDH1A1HIF1A
SCHEMBL14010548 0.79 PTGER2 (0.41) CYP3A4TSHRESR1ESR2AR
SCHEMBL6676894 0.78 ESR1 (0.44) CYP3A4TSHRESR1ESR2AR
SCHEMBL17663780 0.78 HSD11B1 (0.51)
SCHEMBL1155302 0.78 HSD11B1 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638053-B2 crosslinked addition-condensation copolymer contains a polyester endcapped with a vinyl polymerized compound such as acrylic acid, methacrylic acid; use in petroleum industry pervaporation technology to reduce energy costs; stability; for separation of aromatic hydrocarbon from aliphatic hydrocarbon GENERAL ELECTRIC COMPANY (US) 2009-12-29 US claimed
US-20060289352-A1 Poly(meth)acrylate membranes for separation of hydrocarbon mixtures BL TECHNOLOGIES, INC. 2006-12-28 US claimed
US-7638053-B2 crosslinked addition-condensation copolymer contains a polyester endcapped with a vinyl polymerized compound such as acrylic acid, methacrylic acid; use in petroleum industry pervaporation technology to reduce energy costs; stability; for separation of aromatic hydrocarbon from aliphatic hydrocarbon GENERAL ELECTRIC COMPANY (US) 2009-12-29 US disclosed
US-20060289352-A1 Poly(meth)acrylate membranes for separation of hydrocarbon mixtures BL TECHNOLOGIES, INC. 2006-12-28 US disclosed